Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27854864 | 0.90 | PTGER1 (0.50) | CTSVCTSLHPGDPTGER1NPC1 | |
| SCHEMBL5466233 | 0.81 | PKM (0.57) | CTSVCTSLPTPN1PTGER1SMN1; SMN2 | |
| SCHEMBL642897 | 0.80 | KDM4E (0.54) | HPGD | |
| SCHEMBL2317454 | 0.79 | RXRA (0.61) | HPGDNPC1RAB9ASMN1; SMN2SMPD1 | |
| SCHEMBL24140919 | 0.79 | MRGPRX4 (0.51) | CTSVCTSLHPGDNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL16143333 | 0.78 | RXRA (0.60) | HPGDNPC1RAB9ASMN1; SMN2SMPD1 | |
| SCHEMBL18394067 | 0.78 | HPGD (0.56) | CTSVCTSLPTPN1HPGDNPC1 | |
| SCHEMBL30666033 | 0.78 | HPGD (0.56) | CTSVCTSLPTPN1HPGDNPC1 | |
| SCHEMBL3138320 | 0.77 | CTSV (0.57) | CTSVCTSLHPGDNPC1RAB9A | |
| SCHEMBL4728946 | 0.77 | CTSV (0.57) | CTSVCTSLHPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070208164-A1 | Methods of synthesizing radiolabeled 3-cyano[14C]quinolines | WYETH (US) | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208164-A1 | Methods of synthesizing radiolabeled 3-cyano[14C]quinolines | QPCT, RECQL, CBR3 | CTSV 621/4885CTSL 1286/4885PTPN1 4256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.