Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL23525578 | 0.94 | TP53 (0.65) | TP53TSHRLMNASLC7A5 | |
| Lactic Acid SCHEMBL28075168 | 0.92 | TP53 (0.61) | TP53 | |
| Lactic Acid SCHEMBL6117620 | 0.92 | TP53 (0.61) | TP53 | |
| D-Lactic Acid SCHEMBL8220430 | 0.92 | TP53 (0.61) | TP53TSHRLMNASLC7A5 | |
| Lactic Acid SCHEMBL28049778 | 0.86 | TP53 (0.61) | TP53 | |
| Lactic Acid SCHEMBL3889551 | 0.86 | TP53 (0.61) | TP53LMNA | |
| Lactic Acid SCHEMBL26913629 | 0.86 | TP53 (0.61) | TP53LMNA | |
| Lactic Acid SCHEMBL1628145 | 0.84 | TP53 (0.92) | TP53TSHRLMNASLC7A5 | |
| Lactic Acid SCHEMBL32660710 | 0.84 | TP53 (0.92) | TP53TSHRLMNASLC7A5 | |
| Lactic Acid SCHEMBL5364277 | 0.84 | TP53 (0.92) | TP53TSHRLMNASLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106659695-B | Nanoparticles | 赢创罗姆有限公司 | 2019-12-27 | — | — | CN | disclosed |
| US-10172807-B2 | Nanoparticle | EVONIK RÖHM GMBH (DE) | 2019-01-08 | — | — | US | disclosed |
| US-20170333361-A1 | NANOPARTICLE | EVONIK ROEHM GMBH (DE) | 2017-11-23 | — | — | US | disclosed |
| CN-106659695-A | Nanoparticle | 赢创罗姆有限公司 | 2017-05-10 | — | — | CN | disclosed |
| EP-3148515-A1 | NANOPARTICLE | Evonik Röhm GmbH (DE) | 2017-04-05 | — | — | EP | disclosed |
| WO-2015181138-A1 | NANOPARTICLE | EVONIK RÖHM GMBH (DE) | 2015-12-03 | — | — | WO | disclosed |
| CN-201799264-U | Device for preparing polylactic acid and calcium phosphate composite microspheres | JINGMEI WU | 2011-04-20 | — | — | CN | disclosed |
| CN-101293116-A | Absorbent bone interface screw nail and preparation method thereof | LONGSI ZHENG (CN) | 2008-10-29 | — | — | CN | disclosed |
| CN-100381470-C | Method for producing fractionated pectin products | HERCULES INC (US) | 2008-04-16 | — | — | CN | disclosed |
| US-20070116799-A1 | Chewable mass for the remineralization of tooth enamel | MEDERER SUESSWARENVERTRIEBS GMBH (DE) | 2007-05-24 | — | — | US | disclosed |
| CN-1314462-C | Degradable biomedicine composite material in nanometer structure and its prepn process | UNIV ZHEJIANG (CN) | 2007-05-09 | — | — | CN | disclosed |
| CN-1270783-C | Degradable nanometer composite material for biological and medical use | UNIV ZHEJIANG (CN) | 2006-08-23 | — | — | CN | disclosed |
| CN-1672740-A | Degradable biomedicine composite material in nanometer structure and its prepn process | UNIV ZHEJIANG (CN) | 2005-09-28 | — | — | CN | disclosed |
| CN-1485098-A | Degradable nanometer composite material for biological and medical use | 浙江大学 | 2004-03-31 | — | — | CN | disclosed |
| CN-1298413-A | Method for producing fractionated pectin products | HERCULES INC (US) | 2001-06-06 | — | — | CN | disclosed |