Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11557084 | 0.80 | IDO1 (0.60) | IDO1CA1CA2HTTALDH1A1 | |
| SCHEMBL8488722 | 0.79 | IDO1 (0.62) | IDO1CA1CA2HTTF2RL1 | |
| SCHEMBL5028690 | 0.79 | IDO1 (0.62) | IDO1HTTF2RL1EPHX1TAAR1 | |
| SCHEMBL8938869 | 0.78 | IDO1 (0.57) | IDO1HTTALDH1A1F2RL1EPHX1 | |
| SCHEMBL10789554 | 0.77 | IDO1 (0.61) | IDO1CA1CA2HTTALDH1A1 | |
| SCHEMBL22634087 | 0.77 | IDO1 (0.53) | IDO1CA1CA2ALDH1A1TAAR1 | |
| SCHEMBL13905831 | 0.76 | IDO1 (0.59) | IDO1CA1CA2HTTALDH1A1 | |
| SCHEMBL8436880 | 0.76 | IDO1 (0.59) | IDO1HTTF2RL1EPHX1TAAR1 | |
| SCHEMBL10823756 | 0.76 | IDO1 (0.59) | IDO1HTTALDH1A1F2RL1EPHX1 | |
| SCHEMBL5045935 | 0.75 | IDO1 (1.00) | IDO1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2465541-B1 | Improved processes for making hydrazides | WYETH LLC (US) | 2018-07-18 | — | — | EP | disclosed |
| US-9738602-B2 | Processes for making hydrazides | WYETH LLC (US) | 2017-08-22 | — | — | US | disclosed |
| EP-2155258-B1 | IMPROVED PROCESSES FOR MAKING HYDRAZIDES | WYETH LLC (US) | 2017-08-16 | — | — | EP | disclosed |
| US-20160176809-A1 | PROCESSES FOR MAKING HYDRAZIDES | WYETH LLC (US) | 2016-06-23 | — | — | US | disclosed |
| US-9227924-B2 | Processes for making hydrazides | WYETH LLC (US) | 2016-01-05 | — | — | US | disclosed |
| US-20150099865-A1 | PROCESSES FOR MAKING HYDRAZIDES | WYETH LLC (US) | 2015-04-09 | — | — | US | disclosed |
| US-8853451-B2 | Processes for making hydrazides | WYETH LLC (US) | 2014-10-07 | — | — | US | disclosed |
| US-20130211053-A1 | PROCESSES FOR MAKING HYDRAZIDES | WYETH LLC (US) | 2013-08-15 | — | — | US | disclosed |
| US-8383857-B2 | Processes for making hydrazides | WYETH LLC (US) | 2013-02-26 | — | — | US | disclosed |
| EP-2465541-A1 | Improved processes for making hydrazides | Wyeth LLC (US) | 2012-06-20 | — | — | EP | disclosed |
| US-20120130052-A1 | PROCESSES FOR MAKING HYDRAZIDES | WYETH LLC (US) | 2012-05-24 | — | — | US | disclosed |
| US-8110705-B2 | Processes for making hydrazides | WYETH LLC (US) | 2012-02-07 | — | — | US | disclosed |
| US-20080312422-A1 | PROCESSES FOR MAKING HYDRAZIDES | WYETH (US) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312422-A1 | PROCESSES FOR MAKING HYDRAZIDES | CALU, CALD1, ACR | IDO1 4053/4885CA1 37/4885CA2 80/4885 |
| US-20120130052-A1 | PROCESSES FOR MAKING HYDRAZIDES | CALU, CALD1, ACR | IDO1 4053/4885CA1 37/4885CA2 80/4885 |
| US-20130211053-A1 | PROCESSES FOR MAKING HYDRAZIDES | CALU, CALD1, ACR | IDO1 4053/4885CA1 37/4885CA2 80/4885 |
| US-20160176809-A1 | PROCESSES FOR MAKING HYDRAZIDES | CALU, CALD1, ACR | IDO1 4053/4885CA1 37/4885CA2 80/4885 |
| US-20150099865-A1 | PROCESSES FOR MAKING HYDRAZIDES | CALU, CALD1, ACR | IDO1 4053/4885CA1 37/4885CA2 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.