Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131962 | 0.83 | IDO1 (0.54) | IDO1HTTALDH1A1ALOX5LDHA | |
| SCHEMBL8488722 | 0.80 | IDO1 (0.62) | IDO1HTTSMN1; SMN2LDHAF2RL1 | |
| SCHEMBL5028690 | 0.80 | IDO1 (0.62) | IDO1HTTSMN1; SMN2LDHAF2RL1 | |
| SCHEMBL10789554 | 0.79 | IDO1 (0.61) | IDO1HTTALDH1A1SMN1; SMN2LDHA | |
| SCHEMBL10409192 | 0.79 | IDO1 (0.52) | IDO1HTTALDH1A1SMN1; SMN2GAA | |
| SCHEMBL10786759 | 0.79 | ALDH1A1 (0.50) | IDO1HTTALDH1A1SMN1; SMN2ALOX5 | |
| S-Benzyl Dimethylcarbamothioate SCHEMBL7243244 | 0.78 | IDO1 (0.48) | IDO1GAAMEN1KMT2ATAAR1 | |
| SCHEMBL546685 | 0.78 | IDO1 (0.60) | IDO1HTTALDH1A1SMN1; SMN2LDHA | |
| SCHEMBL10823756 | 0.77 | IDO1 (0.59) | IDO1HTTALDH1A1SMN1; SMN2ALOX5 | |
| SCHEMBL8436880 | 0.77 | IDO1 (0.59) | IDO1HTTALOX5LDHAF2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565602-A | REACTING A HYDROCARBYL CHLORIDE WITH A CARBONYL SULFIDE AND AMINE IN PRESENCE OF A BASIC CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1996-10-15 | — | — | US | disclosed |