Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.59 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823756 | 0.86 | IDO1 (0.59) | IDO1HTTLDHAF2RL1EPHX1 | |
| SCHEMBL8488722 | 0.81 | IDO1 (0.62) | IDO1HTTLDHAF2RL1EPHX1 | |
| SCHEMBL5028690 | 0.81 | IDO1 (0.62) | IDO1SAE1UBA2HTTLDHA | |
| SCHEMBL10789554 | 0.80 | IDO1 (0.61) | IDO1SAE1UBA2HTTLDHA | |
| SCHEMBL13905831 | 0.79 | IDO1 (0.59) | IDO1HTTLDHAFFAR1POLB | |
| SCHEMBL8505182 | 0.78 | NPC1 (0.61) | IDO1F2RL1EPHX1ALOX5FFAR1 | |
| SCHEMBL8938869 | 0.77 | IDO1 (0.57) | IDO1HTTLDHAF2RL1EPHX1 | |
| SCHEMBL6571602 | 0.77 | IDO1 (0.67) | IDO1HTTCALM1LTA4HTAAR1 | |
| SCHEMBL9656147 | 0.77 | NPC1 (0.51) | IDO1EPHX1POLB | |
| SCHEMBL11024804 | 0.77 | ALDH1A1 (0.61) | IDO1F2RL1TDP1ALOX5POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994588-A | PROTECTED (AMINOALKYLSULFONYL)ETHYL CARBONATES CONTAINING SULFIDE GROUPS | Funakoshi, Setsuko (JP) | 1999-11-30 | — | — | US | disclosed |
| US-5648462-A | Peptide purification method using novel linker and solid-phase ligand | SETSUKO FUNAKOSHI (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0552368-A1 | PROCESS FOR PURIFYING SYNTHETIC PEPTIDE, AND LINKER AND LINKER-COMBINING SOLID-PHASE CARRIER USED IN SAID PROCESS | NIHON MILLIPORE KABUSHIKI KAISHA (JP) | 1993-07-28 | — | — | EP | disclosed |