Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.53 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5477996 | 0.92 | ADORA1 (0.61) | ADORA3ADORA1ADORA2ACSNK1DIKBKB | |
| SCHEMBL5460119 | 0.89 | ADORA3 (0.53) | ADORA3ADORA1ADORA2ACSNK1DIKBKB | |
| SCHEMBL5465532 | 0.85 | ADORA3 (0.65) | ADORA3ADORA1ADORA2ACYP1A2CYP3A4 | |
| SCHEMBL5460107 | 0.80 | ADORA2A (0.50) | ADORA3ADORA1ADORA2ACSNK1DGAA | |
| SCHEMBL5470769 | 0.79 | PLK1 (0.53) | ADORA3ADORA1ADORA2ACSNK1DGAA | |
| SCHEMBL5473232 | 0.76 | DYRK1A (0.63) | ADORA3ADORA1ADORA2AJAK2JAK3 | |
| SCHEMBL5465546 | 0.76 | GAA (0.69) | ADORA3ADORA1ADORA2AGAAMAPK8 | |
| SCHEMBL5467323 | 0.75 | GAA (0.60) | ADORA3ADORA1ADORA2APIK3CAGAA | |
| SCHEMBL5467334 | 0.74 | NPSR1 (0.64) | ADORA3ADORA1ADORA2AGAADYRK1A | |
| SCHEMBL5468779 | 0.74 | ADORA3 (0.65) | ADORA3ADORA1ADORA2APIK3CAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | NPSR1, MC2R, SRR | ADORA3 187/4885ADORA1 134/4885ADORA2A 307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.