Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5635440 | 0.79 | LMNA (0.39) | TP53ALDH1A1LMNANLRP3 | |
| SCHEMBL5637608 | 0.77 | TP53 (0.46) | TP53 | |
| SCHEMBL9662687 | 0.75 | TP53 (0.56) | TP53 | |
| SCHEMBL23686157 | 0.73 | ALDH1A1 (0.33) | TP53ALDH1A1LMNACYP11B1NLRP3 | |
| SCHEMBL11251469 | 0.73 | PMP22 (0.38) | TP53ALDH1A1LMNANLRP3PMP22 | |
| SCHEMBL17424122 | 0.73 | TP53 (0.54) | TP53LMNA | |
| SCHEMBL17676570 | 0.73 | TP53 (0.54) | TP53LMNA | |
| SCHEMBL15293795 | 0.72 | LMNA (0.43) | TP53ALDH1A1LMNANLRP3 | |
| SCHEMBL13192811 | 0.71 | ALDH1A1 (0.32) | TP53ALDH1A1LMNANLRP3 | |
| SCHEMBL3913999 | 0.71 | ALDH1A1 (0.46) | TP53ALDH1A1LMNANLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9064633-B2 | Method for synthesizing quaternary ammonium systems | HONEYWELL INTERNATIONAL INC. (US) | 2015-06-23 | — | — | US | claimed |
| US-20130264510-A1 | METHOD FOR SYNTHESIZING QUATERNARY AMMONIUM SYSTEMS | HONEYWELL INT INC (US) | 2013-10-10 | — | — | US | claimed |
| US-8426593-B2 | Method for synthesizing quaternary ammonium systems | HONEYWELL INTERNATIONAL INC. (US) | 2013-04-23 | — | — | US | claimed |
| US-20070049750-A1 | Method for synthesizing spiro quartenary ammonium systems | HONEYWELL INTERNATIONAL INC. (US) | 2007-03-01 | — | — | US | claimed |
| EP-0832082-B1 | N-HETEROARYL-PYRIDINESULFONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ASTRAZENECA AB (SE) | 2001-11-21 | — | — | EP | disclosed |
| US-6258817-B1 | PRODRUGS, HYPOTENSIVE AGENTS AND CARDIOVASCULAR DISORDERS | ZENECA LTD. (GB) | 2001-07-10 | — | — | US | disclosed |
| US-6060475-A | Substituted pyrazin-2-yl-sulphonamide-(3-pyridyl) compounds and uses thereof | ZENECA LIMITED (GB) | 2000-05-09 | — | — | US | disclosed |
| US-5866568-A | ENDOTHELIN RECEPTOR ANTAGONIST ACTIVITY | ZENECA LIMITED (GB) | 1999-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049750-A1 | Method for synthesizing spiro quartenary ammonium systems | REN, AGT, PKD1 | TP53 3100/4885ALDH1A1 2665/4885LMNA 2251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.