Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | GPR3 | P46089 | 1/20 | 0.50 |
| ▸ | TOP2A | P11388 | 2/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 4/20 | 0.42 |
| ▸ | GABRD | O14764 | 4/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzo[D]Oxazole SCHEMBL2385440 | 0.82 | NPC1 (0.43) | ALDH1A1HSD17B10GPR3SMN1; SMN2NPC1 | |
| Benzo[D]Oxazole SCHEMBL2724328 | 0.82 | — | — | |
| Benzo[D]Oxazole SCHEMBL7903 | 0.82 | — | — | |
| Benzo[D]Oxazole SCHEMBL27844655 | 0.82 | NPC1 (0.43) | ALDH1A1HSD17B10GPR3SMN1; SMN2NPC1 | |
| Carbazole SCHEMBL7023547 | 0.82 | ALDH1A1 (0.38) | ALDH1A1HSD17B10GPR3TOP2ASMN1; SMN2 | |
| SCHEMBL4150119 | 0.81 | AHR (0.53) | ALDH1A1HSD17B10GPR3TOP2AAHR | |
| SCHEMBL4137851 | 0.81 | AHR (0.53) | ALDH1A1HSD17B10GPR3TOP2AAHR | |
| Benzo[D]Oxazole SCHEMBL16296878 | 0.80 | NPC1 (0.42) | ALDH1A1HSD17B10GPR3SMN1; SMN2NPC1 | |
| Benzo[D]Oxazole SCHEMBL21684956 | 0.80 | NPC1 (0.42) | ALDH1A1HSD17B10GPR3SMN1; SMN2NPC1 | |
| Benzo[D]Oxazole SCHEMBL3619973 | 0.80 | NPC1 (0.42) | ALDH1A1HSD17B10GPR3SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1839129-A | Novel n-substituted indolyl-3-glyoxylic acid amides, use thereof as a medicament, and method for the production thereof | ZENTARIS GMBH (DE) | 2006-09-27 | — | — | CN | claimed |
| CN-111138424-B | Diamine monomer containing benzoxazole and carbazole structures and preparation method and application thereof | 中山大学 | 2021-02-09 | — | — | CN | disclosed |
| CN-111039938-B | Organic electroluminescent material, electronic device and electronic apparatus | 陕西莱特光电材料股份有限公司 | 2021-01-05 | — | — | CN | disclosed |
| CN-111039938-B | Organic electroluminescent material, electronic device and electronic apparatus | 陕西莱特光电材料股份有限公司 | 2021-01-05 | — | — | CN | disclosed |
| CN-111116911-B | Polyimide containing benzoxazole and carbazole structures and preparation method and application thereof | 中山大学 | 2020-12-29 | — | — | CN | disclosed |
| CN-111138424-A | Diamine monomer containing benzoxazole and carbazole structures and preparation method and application thereof | 中山大学 | 2020-05-12 | — | — | CN | disclosed |
| CN-111116911-A | Polyimide containing benzoxazole and carbazole structures and preparation method and application thereof | 中山大学 | 2020-05-08 | — | — | CN | disclosed |
| CN-111039938-A | Organic electroluminescent material, electronic device and electronic apparatus | 陕西莱特光电材料股份有限公司 | 2020-04-21 | — | — | CN | disclosed |
| CN-111039938-A | Organic electroluminescent material, electronic device and electronic apparatus | 陕西莱特光电材料股份有限公司 | 2020-04-21 | — | — | CN | disclosed |
| CN-101508859-B | Aqueous inkjet recording ink | FUJI PHOTO FILM CO LTD | 2013-03-27 | — | — | CN | disclosed |
| US-8110616-B2 | Aqeous inkjet recording ink | FUJIFILM CORPORATION (JP) | 2012-02-07 | — | — | US | disclosed |
| CN-1816543-B | Indole derivatives having apoptosis-inducing effect | ZENTARIS AG | 2011-01-19 | — | — | CN | disclosed |
| EP-2090625-A2 | Aqueous inkjet recording ink | FUJIFILM Corporation (JP) | 2009-08-19 | — | — | EP | disclosed |
| CN-101508859-A | Aqueous inkjet recording ink | FUJIFILM CORP (JP) | 2009-08-19 | — | — | CN | disclosed |
| US-20090203833-A1 | AQEOUS INKJET RECORDING INK | FUJIFILM CORPORATION (JP) | 2009-08-13 | — | — | US | disclosed |
| CN-1839129-A | Novel n-substituted indolyl-3-glyoxylic acid amides, use thereof as a medicament, and method for the production thereof | ZENTARIS GMBH (DE) | 2006-09-27 | — | — | CN | disclosed |
| CN-1816543-A | Indole derivatives having apoptosis-inducing effect | ZENTARIS GMBH (DE) | 2006-08-09 | — | — | CN | disclosed |
| CN-1767896-A | Novel supported catalyst systems | GRACE W R & CO (US) | 2006-05-03 | — | — | CN | disclosed |