Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.38 |
| ▸ | GABRP | O00591 | 3/20 | 0.38 |
| ▸ | GABRD | O14764 | 3/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.38 |
| ▸ | GABRE | P78334 | 3/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.38 |
| ▸ | TDO2 | P48775 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzo[D]Oxazole SCHEMBL6238114 | 0.89 | EGFR (0.36) | SMN1; SMN2NPC1RAB9AMETAP2METAP1 | |
| Carbazole SCHEMBL10734691 | 0.86 | GABRA1 (0.50) | ALDH1A1GABRA1GABRG2GABRB3GABRA5 | |
| Carbazole SCHEMBL6172732 | 0.84 | ALDH1A1 (0.32) | ALDH1A1HSD17B10 | |
| Carbazole SCHEMBL546743 | 0.82 | ALDH1A1 (0.50) | ALDH1A1GABRA1GABRG2GABRB3GABRA5 | |
| Benzimidazole SCHEMBL3704168 | 0.76 | ALDH1A1 (0.36) | ALDH1A1HSD17B10 | |
| Quinoxaline SCHEMBL9450388 | 0.71 | NPC1 (0.39) | ALDH1A1KDM4EHPGDSMN1; SMN2HSD17B10 | |
| Quinoxaline SCHEMBL8664303 | 0.71 | NPC1 (0.39) | ALDH1A1KDM4EHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL4150119 | 0.69 | AHR (0.53) | ALDH1A1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL4137851 | 0.69 | AHR (0.53) | ALDH1A1GABRA1GABRG2GABRB3GABRA5 | |
| Carbazole SCHEMBL28840428 | 0.69 | ALDH1A1 (0.64) | ALDH1A1GABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343766-A1 | CYCLIZATION PROCESS STEP IN THE MAKING OF QUINOLONES AND NAPHTHYRIDINES | THE PROCTER & GAMBLE COMPANY (US) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002048113-A1 | CYCLIZATION PROCESS STEP IN THE MAKING OF QUINOLONES AND NAPHTHYRIDINES | THE PROCTER & GAMBLE COMPANY (US) | 2002-06-20 | — | — | WO | disclosed |