SCHEMBL54677

SCHEMBL54677

CC(=O)c1ccc(F)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.62
CES1 P23141 1/20 0.62
MAOB P27338 2/20 0.60
CA1 P00915 2/20 0.56
CA2 P00918 2/20 0.56
PTGS1 P23219 1/20 0.56
HPGD P15428 2/20 0.54
MAPT P10636 2/20 0.54
RAB9A P51151 2/20 0.54
LMNA P02545 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
KMT2A Q03164 1/20 0.54
ALDH1A1 P00352 1/20 0.53
BCL2L1 Q07817 1/20 0.52
BAD Q92934 1/20 0.52
HSD17B1 P14061 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
HSD11B1 P28845 1/20 0.51
PTPN1 P18031 1/20 0.50
NPC1 O15118 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1696183 1.00 CES2 (0.62) CES2CES1MAOBCA1CA2
Hydrochloric Acid SCHEMBL27523727 0.97 CES2 (0.59) CES2CES1MAOBCA1CA2
Acetic Acid SCHEMBL28372390 0.95 CES2 (0.56) CES2CES1MAOBCA1CA2
Boric Acid SCHEMBL29051484 0.93 MAOB (0.55) CES2CES1MAOBCA1CA2
SCHEMBL7937485 0.93 LTA4H (0.59) CES2CES1MAOBCA1CA2
SCHEMBL4448294 0.93 SMN1; SMN2 (0.64) CES2CES1MAOBCA1CA2
Acetohydroxamic Acid SCHEMBL28835704 0.89 MAOB (0.51) CES2CES1MAOBCA1CA2
SCHEMBL3370005 0.87 HPGD (0.79) CES2CES1MAOBCA1CA2
SCHEMBL7938515 0.87 KMT2A (0.79) CES2CES1MAOBCA1CA2
SCHEMBL3138940 0.87 HPGD (0.79) CES2CES1MAOBPTGS1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4210 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117832491-B Positive electrode additive, preparation method thereof, positive electrode plate, secondary battery and battery pack Xiamen Haichen Energy Storage Technology Co.,Ltd. (CN) 2026-05-26 CN claimed
EP-4581071-A1 METHOD FOR PRODUCING A MATERIAL FOR A MEMBRANE, MATERIAL, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2025-07-09 EP claimed
CN-119926191-B Conjugated microporous organic solvent-resistant nanofiltration composite membrane and preparation method and application thereof 中山大学 2025-06-13 CN claimed
CN-119859095-B Diphenyl ether chalcone derivative and preparation method and application thereof 四川大学 2025-06-03 CN claimed
CN-119926191-A Conjugated microporous organic solvent-resistant nanofiltration composite membrane and preparation method and application thereof 中山大学 2025-05-06 CN claimed
US-20250136445-A1 HYDROGEN PEROXIDE MANUFACTURING PROCESS AND MANUFACTURING SYSTEM BASED ON PHOTOCHEMICAL REACTION KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2025-05-01 US claimed
CN-119859095-A Diphenyl ether chalcone derivative and preparation method and application thereof 四川大学 2025-04-22 CN claimed
CN-119776306-A Carbonyl reductase mutant and application thereof in synthesis of chiral alcohol compound 浙江工业大学 2025-04-08 CN claimed
CN-119684071-A Para-terphenyl derivative and synthesis method thereof 湖南大学 2025-03-25 CN claimed
CN-119409630-A Asymmetric polyfluoro-substituted 2,4' -biquinoline-4-amide derivative and preparation method and application thereof 郑州工业应用技术学院 2025-02-11 CN claimed
US-5892053-A Process for preparing 3-haloalkyl-1H-pyrazoles G. D. SEARLE & CO. (US) 1999-04-06 US claimed
US-5783164-A PALLADIUM CATALYST WITH A NITROGENATED LIGAND STABLE TO OXIDATION ENICHEM S.P.A. (IT) 1998-07-21 US claimed
EP-0853064-A1 Process for the synthesis of hydrogen peroxide ENICHEM S.p.A. (IT) 1998-07-15 EP claimed
EP-0828717-A1 METHOD OF PREPARING 3-HALOALKYL-1H-PYRAZOLES G.D. SEARLE & CO. (US) 1998-03-18 EP claimed
EP-0808796-A1 Process for the preparation of hydrogen peroxide ENICHEM S.p.A. (IT) 1997-11-26 EP claimed
WO-1996037476-A1 METHOD OF PREPARING 3-HALOALKYL-1H-PYRAZOLES G.D. SEARLE & CO. (US) 1996-11-28 WO claimed
US-5532374-A Method of preparation of bis-quinolines HITACHI CHEMICAL COMPANY, LTD. (JP) 1996-07-02 US claimed
EP-0243000-B1 POLYCYANOARYL ETHER, METHOD FOR PREPARING THE SAME AND USES THEREOF IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-10-03 EP claimed
EP-0243000-A1 Polycyanoaryl ether, method for preparing the same and uses thereof IDEMITSU KOSAN COMPANY LIMITED (JP) 1987-10-28 EP claimed
US-4075340-A ANTIINFLAMMATORY, ANTIARRYTHMIC, ANTICOAGULANTS PARCOR (FR) 1978-02-21 US claimed