Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.79 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | MAOB | P27338 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859304 | 0.89 | KMT2A (1.00) | KMT2ALMNAMAOBRAB9AMAPT | |
| SCHEMBL12243153 | 0.88 | MAOB (0.64) | KMT2ALMNAMAOBALDH1A1NPC1 | |
| SCHEMBL1696183 | 0.87 | CES2 (0.62) | KMT2ALMNAMAOBALDH1A1NPC1 | |
| SCHEMBL54677 | 0.87 | CES2 (0.62) | KMT2ALMNAMAOBALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL27523727 | 0.84 | CES2 (0.59) | KMT2ALMNAMAOBALDH1A1NPC1 | |
| SCHEMBL8577031 | 0.83 | LTA4H (0.57) | KMT2ALMNAALDH1A1NPC1RAB9A | |
| SCHEMBL9018906 | 0.83 | LTA4H (0.57) | KMT2ALMNAALDH1A1NPC1RAB9A | |
| Acetic Acid SCHEMBL28372390 | 0.82 | CES2 (0.56) | KMT2ALMNAMAOBALDH1A1NPC1 | |
| SCHEMBL16864582 | 0.81 | KMT2A (0.83) | KMT2ALMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2688501 | 0.81 | KMT2A (0.83) | KMT2ALMNAMAOBMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |