Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28122613 | 0.94 | MCHR1 (0.44) | CA2CA9CA12ALDH1A1LMNA | |
| SCHEMBL2903624 | 0.94 | MCHR1 (0.44) | CA2CA9CA12ALDH1A1LMNA | |
| SCHEMBL1545381 | 0.90 | CA2 (0.47) | CA2CA9CA12ALDH1A1LMNA | |
| SCHEMBL1545377 | 0.90 | CA2 (0.47) | CA2CA9CA12ALDH1A1LMNA | |
| SCHEMBL1545434 | 0.90 | CA2 (0.47) | CA2CA9CA12ALDH1A1LMNA | |
| SCHEMBL7143782 | 0.88 | ALDH1A1 (0.40) | CA2CA9CA12ALDH1A1CYP2C9 | |
| SCHEMBL11305845 | 0.86 | TDP1 (0.46) | CA2CA9ALDH1A1TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL9501772 | 0.85 | ALDH1A1 (0.38) | CA2CA9CA12ALDH1A1CYP2C9 | |
| SCHEMBL5551724 | 0.84 | PPARG (0.41) | CA2CA9CA12ALDH1A1CYP2C9 | |
| SCHEMBL31344867 | 0.84 | CA12 (0.44) | CA2CA9CA12ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970327-B1 | OXABICYCLO [2.2.2]ACID GPR120 MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2017-05-03 | — | — | EP | disclosed |
| EP-2970327-A1 | OXABICYCLO [2.2.2]ACID GPR120 MODULATORS | Bristol-Myers Squibb Company (US) | 2016-01-20 | — | — | EP | disclosed |
| US-8962660-B2 | Oxabicyclo [2.2.2] acid GPR120 modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-02-24 | — | — | US | disclosed |
| WO-2014151247-A1 | OXABICYCLO [2.2.2] ACID GPR120 MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-09-25 | — | — | WO | disclosed |
| US-20140275173-A1 | OXABICYCLO [2.2.2] ACID GPR120 MODULATORS | BRISTOL-MYERS SQUIBB COMPANY | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275173-A1 | OXABICYCLO [2.2.2] ACID GPR120 MODULATORS | GPR180, GPR52, GPR55 | CA2 488/4885CA9 3376/4885CA12 2301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.