Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA known ✓ | P35790 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5028519 | 0.98 | — | — | |
| SCHEMBL28334358 | 0.81 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10MAOA | |
| SCHEMBL28336431 | 0.78 | HTT (0.46) | KDM4EALDH1A1 | |
| Bromide SCHEMBL9654786 | 0.77 | HSP90AA1 (0.56) | ALDH1A1KMT2A | |
| Bromide SCHEMBL557020 | 0.76 | PABPC1 (0.51) | KDM4EALDH1A1PABPC1KMT2AATM | |
| SCHEMBL10646216 | 0.75 | HTT (0.56) | KMT2A | |
| SCHEMBL11356827 | 0.75 | HTT (0.56) | KMT2A | |
| SCHEMBL2737196 | 0.75 | KDM4E (0.51) | KDM4EPKMAPOBEC3AAPOBEC3G | |
| Bromide SCHEMBL7969935 | 0.74 | KDM4E (0.62) | KDM4EALDH1A1PKMAPOBEC3AAPOBEC3G | |
| Bromide SCHEMBL2421505 | 0.74 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3308962-B1 | INKJET INK, INK CARTRIDGE, INKJET RECORDING METHOD, INKJET RECORDING DEVICE, AND INKJET RECORDED MATTER | RICOH CO LTD (JP) | 2020-11-11 | — | — | EP | disclosed |
| EP-2052044-B1 | RECORDING INK, INK CARTRIDGE, INK MEDIA SET, INK- JET RECORDING METHOD AND INK-JET RECORDING APPARATUS | RICOH CO LTD (JP) | 2019-02-06 | — | — | EP | disclosed |
| EP-3308962-A1 | INKJET INK, INK CARTRIDGE, INKJET RECORDING METHOD, INKJET RECORDING DEVICE, AND INKJET RECORDED MATTER | Ricoh Company Ltd. (JP) | 2018-04-18 | — | — | EP | disclosed |
| EP-2686393-B1 | INKJET INK, INKJET RECORDING METHOD, AND INKJET RECORDING DEVICE | RICOH CO LTD (JP) | 2018-02-07 | — | — | EP | disclosed |
| EP-2601271-B1 | INKJET INK, INK CARTRIDGE, INKJET RECORDING METHOD, INKJET RECORDING DEVICE, AND INKJET RECORDED MATTER | RICOH CO LTD (JP) | 2018-01-24 | — | — | EP | disclosed |
| EP-2809734-B1 | INKJET INK AND INKJET RECORDING DEVICE | RICOH CO LTD (JP) | 2017-10-18 | — | — | EP | disclosed |
| EP-2178992-B1 | RECORDING INK, INK MEDIA SET, INK CARTRIDGE, INK RECORDED MATTER, INKJET RECORDING APPARATUS, AND INKJET RECORDING METHOD | RICOH CO LTD (JP) | 2017-01-25 | — | — | EP | disclosed |
| EP-2614964-B1 | Image forming method | RICOH CO LTD (JP) | 2017-01-04 | — | — | EP | disclosed |
| US-9528017-B2 | Inkjet ink and inkjet recording device | RICOH COMPANY, LTD. (JP) | 2016-12-27 | — | — | US | disclosed |
| US-9518190-B2 | Inkjet ink, ink cartridge, inkjet recording method, inkjet recording device, and inkjet recorded matter | RICOH COMPANY, LTD. (JP) | 2016-12-13 | — | — | US | disclosed |
| EP-0947567-A1 | Ink, ink set, ink cartridge, recording unit, image recording process and image recording apparatus | CANON KABUSHIKI KAISHA (JP) | 1999-10-06 | — | — | EP | disclosed |
| EP-0943666-A2 | Ink, ink set, ink cartridge, recording unit, image recording apparatus and image recording method | CANON KABUSHIKI KAISHA (JP) | 1999-09-22 | — | — | EP | disclosed |
| US-5900029-A | COLORING FIBER OR TEXTILE | CABOT CORPORATION (US) | 1999-05-04 | — | — | US | disclosed |
| US-5851280-A | Reaction of carbon black with diazonium salts, resultant carbon black products and their uses | CABOT CORPORATION (US) | 1998-12-22 | — | — | US | disclosed |
| EP-0879857-A2 | Ink set, and recording method and recording instrument using the same | CANON KABUSHIKI KAISHA (JP) | 1998-11-25 | — | — | EP | disclosed |
| EP-0842994-A1 | Water-based pigment ink, and ink-jet recording method and instruments using the same | CANON KABUSHIKI KAISHA (JP) | 1998-05-20 | — | — | EP | disclosed |
| EP-0799281-A1 | CARBON BLACK REACTED WITH DIAZONIUM SALTS AND PRODUCTS | CABOT CORPORATION (US) | 1997-10-08 | — | — | EP | disclosed |
| US-5630868-A | REACTED WITH DIAZONIUM SALT; PRINT QUALITY | CABOT CORPORATION (US) | 1997-05-20 | — | — | US | disclosed |
| WO-1996018688-A1 | CARBON BLACK REACTED WITH DIAZONIUM SALTS AND PRODUCTS | CABOT CORPORATION (US) | 1996-06-20 | — | — | WO | disclosed |
| WO-1996018695-A1 | INK JET INK FORMULATIONS CONTAINING MODIFIED CARBON PRODUCTS | CABOT CORPORATION (US) | 1996-06-20 | — | — | WO | disclosed |