Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29556923 | 0.98 | — | — | |
| SCHEMBL294294 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL557275 | 0.95 | PABPC1 (0.47) | PABPC1KMT2AATMLMNAL3MBTL1 | |
| Fluoride Ion SCHEMBL30212627 | 0.95 | PABPC1 (0.47) | PABPC1KMT2AATMLMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL30330570 | 0.95 | PABPC1 (0.47) | PABPC1KMT2AATMLMNAL3MBTL1 | |
| Water SCHEMBL15375305 | 0.95 | PABPC1 (0.47) | PABPC1KMT2AATMLMNAL3MBTL1 | |
| Iodide SCHEMBL4324715 | 0.95 | KMT2A (0.47) | PABPC1KMT2AATMLMNAL3MBTL1 | |
| SCHEMBL15535626 | 0.91 | PABPC1 (0.49) | PABPC1KMT2AATMLMNAL3MBTL1 | |
| SCHEMBL28433763 | 0.90 | PABPC1 (0.44) | PABPC1KMT2AATMLMNAL3MBTL1 | |
| SCHEMBL1462014 | 0.90 | PABPC1 (0.44) | PABPC1KMT2AATMLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190198881-A1 | ELECTROLYTE FOR RECHARGEABLE ELECTROCHEMICAL CELL | EOS ENERGY STORAGE LLC | 2019-06-27 | — | — | US | claimed |
| US-10276872-B2 | Electrolyte for rechargeable electrochemical cell | EOS ENERGY STORAGE, LLC (US) | 2019-04-30 | — | — | US | claimed |
| CN-105026371-B | Process for preparing 1-alkyl-3-alkyl-pyridinium bromides and their use as additives in electrochemical cells | 溴化合物有限公司 | 2018-08-28 | — | — | CN | claimed |
| US-20180151905-A1 | ADDITIVES FOR HYDROGEN/BROMINE CELLS | BROMINE COMPOUNDS LTD. (IL) | 2018-05-31 | — | — | US | claimed |
| US-9905874-B2 | Additives for hydrogen/bromine cells | BROMINE COMPOUNDS LTD. (IL) | 2018-02-27 | — | — | US | claimed |
| US-9722281-B2 | Processes for preparing 1-alkyl-3-alkyl-pyridinium bromide and uses thereof as additives in electrochemical cells | BROMINE COMPOUNDS LTD. (IL) | 2017-08-01 | — | — | US | claimed |
| US-20170194666-A1 | ELECTROLYTE FOR RECHARGEABLE ELECTROCHEMICAL CELL | CITIBANK, N.A., AS COLLATERAL AGENT | 2017-07-06 | — | — | US | claimed |
| EP-2759016-B1 | ADDITIVES FOR HYDROGEN/ BROMINE CELLS | BROMINE COMPOUNDS LTD (IL) | 2017-03-29 | — | — | EP | claimed |
| EP-2758373-B1 | PROCESSES FOR PREPARING N-ETHYL-2-METHYLPYRIDINIUM BROMIDE AND N-ETHYL-3-METHYLPYRIDINIUM BROMIDE | BROMINE COMPOUNDS LTD (IL) | 2017-03-22 | — | — | EP | claimed |
| EP-2953930-B1 | PROCESSES FOR PREPARING 1-ALKYL-3-ALKYL-PYRIDINIUM BROMIDE AND USES THEREOF AS ADDITIVES IN ELECTROCHEMICAL CELLS | BROMINE COMPOUNDS LTD (IL) | 2016-12-07 | — | — | EP | claimed |
| US-20150372351-A1 | PROCESSES FOR PREPARING L-ALKYL-3-ALKYL-PYRIDINIUM BROMIDE AND USES THEREOF AS ADDITIVES IN ELECTROCHEMICAL CELLS | BROMINE COMPOUNDS LTD. (IL) | 2015-12-24 | — | — | US | claimed |
| EP-2953930-A1 | PROCESSES FOR PREPARING L-ALKYL-3-ALKYL-PYRIDINIUM BROMIDE AND USES THEREOF AS ADDITIVES IN ELECTROCHEMICAL CELLS | Bromine Compounds Ltd. (IL) | 2015-12-16 | — | — | EP | claimed |
| CN-105026371-A | Process for preparing 1-alkyl-3-alkyl-pyridinium bromides and their use as additives in electrochemical cells | BROMINE COMPOUNDS LTD | 2015-11-04 | — | — | CN | claimed |
| US-20140302408-A1 | ADDITIVES FOR HYDROGEN/BROMINE CELLS | BROMINE COMPOUNDS LTD. (IL) | 2014-10-09 | — | — | US | claimed |
| US-20140262818-A1 | PROCESSES FOR PREPARING N-ETHYL-2-METHYLPYRIDINIUM BROMIDE AND N-ETHYL-3-METHYLPYRIDINIUM BROMIDE | BROMINE COMPOUNDS LTD. (IL) | 2014-09-18 | — | — | US | claimed |
| WO-2014122641-A1 | PROCESSES FOR PREPARING L-ALKYL-3-ALKYL-PYRIDINIUM BROMIDE AND USES THEREOF AS ADDITIVES IN ELECTROCHEMICAL CELLS | BROMINE COMPOUNDS LTD. (IL) | 2014-08-14 | — | — | WO | claimed |
| EP-2759016-A1 | ADDITIVES FOR HYDROGEN/ BROMINE CELLS | Bromine Compounds Ltd. (IL) | 2014-07-30 | — | — | EP | claimed |
| EP-2758373-A1 | PROCESSES FOR PREPARING N-ETHYL-2-METHYLPYRIDINIUM BROMIDE AND N-ETHYL-3-METHYLPYRIDINIUM BROMIDE | Bromine Compounds Ltd. (IL) | 2014-07-30 | — | — | EP | claimed |
| WO-2013042109-A1 | PROCESSES FOR PREPARING N-ETHYL-2-METHYLPYRIDINIUM BROMIDE AND N-ETHYL-3-METHYLPYRIDINIUM BROMIDE | BROMINE COMPOUNDS LTD. (IL) | 2013-03-28 | — | — | WO | claimed |
| WO-2013042110-A1 | ADDITIVES FOR HYDROGEN/ BROMINE CELLS | BROMINE COMPOUNDS LTD. (IL) | 2013-03-28 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150372351-A1 | PROCESSES FOR PREPARING L-ALKYL-3-ALKYL-PYRIDINIUM BROMIDE AND USES THEREOF AS ADDITIVES IN ELECTROCHEMICAL CELLS | PLP2, PLPBP, AZI2 | PABPC1 1480/4885KMT2A 971/4885ATM 1892/4885 |
| US-20140262818-A1 | PROCESSES FOR PREPARING N-ETHYL-2-METHYLPYRIDINIUM BROMIDE AND N-ETHYL-3-METHYLPYRIDINIUM BROMIDE | MEP1B, MEP1A, EDNRB | PABPC1 3149/4885KMT2A 1806/4885ATM 2721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.