Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | GALK1 | P51570 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ERO1A | Q96HE7 | 2/20 | 0.47 |
| ▸ | EP300 | Q09472 | 2/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 5/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5468614 | 1.00 | MEN1 (0.51) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL5476639 | 0.88 | ERO1A (0.58) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL5476898 | 0.84 | KMT2A (0.58) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL5476893 | 0.84 | KMT2A (0.58) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL5469970 | 0.78 | MEN1 (0.83) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL5469976 | 0.78 | MEN1 (0.83) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL419547 | 0.72 | KMT2A (0.60) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL445330 | 0.72 | KMT2A (0.60) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL419548 | 0.71 | ERO1A (0.83) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL444011 | 0.71 | ERO1A (0.83) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC. (JP) | 2007-11-29 | — | — | US | disclosed |
| EP-1666469-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | Institute of Medicinal Molecular Design, Inc. (JP) | 2006-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | SERPINE1, SERPINC1, SERPINB1 | MEN1 2892/4885KMT2A 2948/4885L3MBTL1 1479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.