Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL966496 | 0.82 | ALDH1A1 (0.54) | MEN1KMT2AHSD17B1HSD17B2ALDH1A1 | |
| SCHEMBL30181119 | 0.82 | ALDH1A1 (0.54) | MEN1KMT2AHSD17B1HSD17B2ALDH1A1 | |
| SCHEMBL607945 | 0.81 | HSD17B10 (0.44) | MEN1KMT2AHSD17B1HSD17B2NR1H2 | |
| Hydrochloric Acid SCHEMBL31579091 | 0.81 | CRBN (0.34) | CRBNMEN1KMT2ASTING1FFAR1 | |
| SCHEMBL26690754 | 0.80 | ALDH1A1 (0.42) | MEN1KMT2AHSD17B1HSD17B2ALDH1A1 | |
| SCHEMBL2831221 | 0.80 | KDM4E (0.45) | CRBNMEN1KMT2AHSD17B1HSD17B2 | |
| SCHEMBL27927680 | 0.80 | HSD17B10 (0.43) | MEN1KMT2AHSD17B1HSD17B2NR1H2 | |
| SCHEMBL30194898 | 0.79 | PTPN1 (0.38) | CRBNALDH1A1SMN1; SMN2 | |
| SCHEMBL1187294 | 0.79 | PTPN1 (0.38) | CRBNALDH1A1SMN1; SMN2 | |
| Methylene Chloride SCHEMBL28420789 | 0.79 | HSD17B10 (0.40) | MEN1KMT2AHSD17B1HSD17B2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114716373-B | Preparation method of gatifloxacin cyclized ester | 内蒙古源宏精细化工有限公司 | 2023-01-10 | — | — | CN | disclosed |
| CN-114716373-A | Preparation method of gatifloxacin cyclized ester | 内蒙古源宏精细化工有限公司 | 2022-07-08 | — | — | CN | disclosed |
| WO-2014185881-A1 | METHOD FOR PRODUCING (1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-8-METHOXY-7-[(4AS,7AS)-OCTAHYDRO-6H-PYRROLO[3,4-B]PYRIDIN-6-YL]-4-OXO-3-QUINOLINE-CARBOXYLIC ACID | DERKACH NATALIIA MYKOLAIVNA (UA) | 2014-11-20 | — | — | WO | disclosed |
| US-20070254866-A1 | Aminoquinolones as GSK-3 inhibitors | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254866-A1 | Aminoquinolones as GSK-3 inhibitors | GSK3B, GSK3A, GSKIP | CRBN 2049/4885MEN1 4540/4885KMT2A 539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.