SCHEMBL5469559

SCHEMBL5469559

COc1ccc(O)c(Cl)c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.52
MAPT P10636 3/20 0.52
TP53 P04637 2/20 0.52
CYP3A4 P08684 2/20 0.52
KDM4E B2RXH2 2/20 0.52
ALDH1A1 P00352 2/20 0.52
LMNA P02545 1/20 0.52
HPGD P15428 1/20 0.52
ALOX15 P16050 1/20 0.52
ALOX12 P18054 1/20 0.52
HSD17B10 Q99714 1/20 0.52
HIF1A Q16665 1/20 0.48
EPAS1 Q99814 1/20 0.48
MAOB P27338 1/20 0.45
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
TSHR P16473 1/20 0.43
KMT2A Q03164 2/20 0.41
ERN1 O75460 2/20 0.40
RAB9A P51151 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11151784 0.84 MAPK1 (0.48) MAPK1MAPTTP53CYP3A4KDM4E
SCHEMBL9335491 0.82 MAPK1 (0.46) MAPK1MAPTTP53CYP3A4KDM4E
SCHEMBL28436581 0.82 HIF1A (0.53) MAPK1MAPTTP53CYP3A4KDM4E
SCHEMBL12957854 0.80 MAPT (0.45) MAPK1MAPTTP53CYP3A4KDM4E
SCHEMBL9035273 0.80 MAPT (0.44) MAPK1MAPTTP53CYP3A4KDM4E
SCHEMBL16704713 0.78 MAPT (0.43) MAPK1MAPTTP53CYP3A4KDM4E
SCHEMBL6571131 0.78 IDO1 (0.44) MAPK1MAPTTP53CYP3A4KDM4E
SCHEMBL5979424 0.78 HIF1A (0.50) MAPK1MAPTTP53CYP3A4KDM4E
SCHEMBL18544403 0.78 MAOB (0.42) MAPK1MAPTTP53CYP3A4KDM4E
SCHEMBL9742294 0.78 KDM4E (0.65) MAPK1MAPTTP53CYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112843027-B Application of 2-chloro-6-methoxyresorcinol in inhibiting mycobacterium tuberculosis tyrosine phosphatase A 中山大学 2022-08-09 CN claimed
CN-112843027-A Application of 2-chloro-6-methoxyresorcinol in inhibiting mycobacterium tuberculosis tyrosine phosphatase A 中山大学 2021-05-28 CN claimed
CN-108299483-A The borate detected for glycoprotein and the method for preparing the borate 广东优尼德生物科技有限公司 2018-07-20 CN claimed
CN-108191900-A Borate for glycoprotein detection and preparation method thereof 广东优尼德生物科技有限公司 2018-06-22 CN claimed
CN-112843027-B Application of 2-chloro-6-methoxyresorcinol in inhibiting mycobacterium tuberculosis tyrosine phosphatase A 中山大学 2022-08-09 CN disclosed
CN-112843027-B Application of 2-chloro-6-methoxyresorcinol in inhibiting mycobacterium tuberculosis tyrosine phosphatase A 中山大学 2022-08-09 CN disclosed
CN-112843027-B Application of 2-chloro-6-methoxyresorcinol in inhibiting mycobacterium tuberculosis tyrosine phosphatase A 中山大学 2022-08-09 CN disclosed
CN-112843027-A Application of 2-chloro-6-methoxyresorcinol in inhibiting mycobacterium tuberculosis tyrosine phosphatase A 中山大学 2021-05-28 CN disclosed
CN-112843027-A Application of 2-chloro-6-methoxyresorcinol in inhibiting mycobacterium tuberculosis tyrosine phosphatase A 中山大学 2021-05-28 CN disclosed
CN-112843027-A Application of 2-chloro-6-methoxyresorcinol in inhibiting mycobacterium tuberculosis tyrosine phosphatase A 中山大学 2021-05-28 CN disclosed
CN-108299483-A The borate detected for glycoprotein and the method for preparing the borate 广东优尼德生物科技有限公司 2018-07-20 CN disclosed
CN-108191900-A Borate for glycoprotein detection and preparation method thereof 广东优尼德生物科技有限公司 2018-06-22 CN disclosed
US-5840999-A NAPHTHOL INTERMEDIATES FOR FLUORESCENT DYES THE PERKIN-ELMER CORPORATION (US) 1998-11-24 US disclosed
WO-1997036960-A1 ASYMMETRIC BENZOXANTHENE DYES THE PERKIN-ELMER CORPORATION (US) 1997-10-09 WO disclosed
US-4652531-A Fluorescent protein binding assays with unsymmetrical fluorescein derivatives SYNTEX (U.S.A.) INC. (US) 1987-03-24 US disclosed
EP-0050684-B1 NOVEL ETHER SUBSTITUTED FLUORESCEIN COMPOUNDS AS FLUORESCERS AND QUENCHERS SYVA COMPANY (US) 1986-01-22 EP disclosed
US-4439356-A XANTHENES, IMMUNOASSAY SYVA COMPANY (US) 1984-03-27 US disclosed
US-4329461-A Fluorescent thyroid hormone conjugates and their uses SYVA COMPANY (US) 1982-05-11 US disclosed
EP-0050684-A1 Novel ether substituted fluorescein compounds as fluorescers and quenchers SYVA COMPANY (US) 1982-05-05 EP disclosed
US-4318846-A RADIOIMMUNOASSAY SYVA COMPANY (US) 1982-03-09 US disclosed