Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.42 |
| ▸ | TUBB | P07437 | 4/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70469 | 0.84 | CYP3A4 (0.44) | MAPTTDP1MAOBTP53CYP3A4 | |
| SCHEMBL11151784 | 0.82 | MAPK1 (0.48) | MAPTTDP1MAOBHIF1AEPAS1 | |
| SCHEMBL5469559 | 0.80 | MAPK1 (0.52) | MAPTMAOBHIF1AEPAS1TUBB1 | |
| SCHEMBL1402414 | 0.79 | MAPT (0.48) | MAPTTDP1MAOBHIF1AEPAS1 | |
| SCHEMBL3384067 | 0.78 | CYP3A4 (0.39) | TDP1MAOBHIF1AEPAS1TUBB1 | |
| SCHEMBL8990966 | 0.77 | HTR2A (0.43) | MAPTTDP1TUBB1TUBB4ATUBB | |
| SCHEMBL70595 | 0.77 | MAPT (0.57) | MAPTTDP1MAOBHIF1AEPAS1 | |
| SCHEMBL27770681 | 0.77 | MAPT (0.47) | MAPTTDP1MAOBHIF1AEPAS1 | |
| SCHEMBL5979424 | 0.77 | HIF1A (0.50) | MAPTMAOBHIF1AEPAS1TP53 | |
| SCHEMBL18544403 | 0.77 | MAOB (0.42) | MAPTMAOBHIF1AEPAS1TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1143366-A | 4-mycophenolic acid-amino derivatives | SYNTEX INC (US) | 1997-02-19 | — | — | CN | disclosed |
| EP-0745074-A1 | 4-AMINO DERIVATIVES OF MYCOPHENOLIC ACID WITH IMMUNOSUPPRESSANT ACTIVITY | SYNTEX (U.S.A.) INC. (US) | 1996-12-04 | — | — | EP | disclosed |
| WO-1995022535-A1 | 4-AMINO DERIVATIVES OF MYCOPHENOLIC ACID WITH IMMUNOSUPPRESSANT ACTIVITY | SYNTEX (U.S.A.) INC. (US) | 1995-08-24 | — | — | WO | disclosed |
| US-5441953-A | Immunosuppressants | SYNTEX (U.S.A.) INC. (US) | 1995-08-15 | — | — | US | disclosed |
| US-5380879-A | Immunosuppressants | SYNTEX (U.S.A.) INC. (US) | 1995-01-10 | — | — | US | disclosed |