Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PAM | P19021 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.36 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.36 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL27725386 | 0.80 | ALDH1A1 (0.74) | ALDH1A1TSHRMCL1LMNASMN1; SMN2 | |
| Styrene SCHEMBL9011439 | 0.80 | ALDH1A1 (0.74) | ALDH1A1TSHRPAMMCL1LMNA | |
| Styrene SCHEMBL4375720 | 0.79 | ALDH1A1 (0.58) | ALDH1A1TSHRPAMMCL1LMNA | |
| Styrene SCHEMBL5859639 | 0.78 | ALDH1A1 (0.64) | ALDH1A1TSHRPAMMCL1LMNA | |
| Styrene SCHEMBL26133544 | 0.78 | ALDH1A1 (0.64) | ALDH1A1TSHRPAMLMNAMEN1 | |
| Styrene SCHEMBL5480221 | 0.78 | ALDH1A1 (0.64) | ALDH1A1TSHRPAMLMNASMN1; SMN2 | |
| Biphenyl SCHEMBL31235587 | 0.78 | MCL1 (0.48) | ALDH1A1TSHRMCL1LMNASMN1; SMN2 | |
| Styrene SCHEMBL27928437 | 0.78 | ALDH1A1 (0.70) | ALDH1A1TSHRMCL1LMNASMN1; SMN2 | |
| Styrene SCHEMBL27636982 | 0.78 | ALDH1A1 (0.70) | ALDH1A1TSHRMCL1LMNASMN1; SMN2 | |
| Styrene SCHEMBL27849673 | 0.78 | ALDH1A1 (0.70) | ALDH1A1TSHRMCL1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110536944-A | Formaldehyde-free curable compositions | ROHM & HAAS | 2019-12-03 | — | — | CN | disclosed |
| US-20070014756-A1 | Composition and method for treating the gastro-intestinal tract | TOUCHOT NICHOLAS | 2007-01-18 | — | — | US | disclosed |
| US-20040191318-A1 | Composition and method for treating the gastro-intestinal tract | VILLITECH SARL (FR) | 2004-09-30 | — | — | US | disclosed |
| EP-1462116-A1 | Composition for treating the gastrointestinal tract | Villitech SARL (FR) | 2004-09-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070014756-A1 | Composition and method for treating the gastro-intestinal tract | GIPR, FABP2, FABP6 | ALDH1A1 3713/4885TSHR 334/4885PAM 298/4885 |
| US-20040191318-A1 | Composition and method for treating the gastro-intestinal tract | GIPR, FABP2, FABP6 | ALDH1A1 3713/4885TSHR 334/4885PAM 298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.