Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 2/20 | 0.32 |
| ▸ | CPA1 | P15085 | 2/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.32 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | ACR | P10323 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5458732 | 0.93 | ALDH1A1 (0.36) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL5465853 | 0.87 | CYP2C19 (0.47) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL5466084 | 0.79 | ACE (0.36) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL5473337 | 0.77 | LAP3 (0.43) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL5466128 | 0.76 | USP2 (0.36) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL5466076 | 0.76 | TDP1 (0.44) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL5464540 | 0.74 | ACE (0.42) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL5090467 | 0.74 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL5470263 | 0.74 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL5470269 | 0.74 | FNTA (0.43) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070009462-A9 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | MALLE GERARD | 2007-01-11 | — | — | US | claimed |
| US-20050201964-A1 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | L'OREAL S.A. (FR) | 2005-09-15 | — | — | US | claimed |
| US-20070009462-A9 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | MALLE GERARD | 2007-01-11 | — | — | US | disclosed |
| US-20050201964-A1 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | L'OREAL S.A. (FR) | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050201964-A1 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | NR5A1, SRD5A2, HRH3 | ALDH1A1 792/4885LMNA 2678/4885MAPT 3323/4885 |
| US-20070009462-A9 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | NR5A1, SRD5A2, HRH3 | ALDH1A1 792/4885LMNA 2678/4885MAPT 3323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.