Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 3/20 | 0.43 |
| ▸ | ANPEP | P15144 | 4/20 | 0.42 |
| ▸ | DNPEP | Q9ULA0 | 3/20 | 0.42 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.38 |
| ▸ | CAPN9 | O14815 | 2/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5466128 | 0.82 | USP2 (0.36) | L3MBTL1LMNAALDH1A1MAPTPTGS2 | |
| SCHEMBL5465853 | 0.82 | CYP2C19 (0.47) | RNPEPHPGDLMNAALDH1A1MAPT | |
| SCHEMBL5470263 | 0.80 | ALDH1A1 (0.47) | LMNAALDH1A1MAPTPTGS2TDP1 | |
| SCHEMBL5470269 | 0.79 | FNTA (0.43) | SMN1; SMN2LMNA | |
| SCHEMBL5466084 | 0.78 | ACE (0.36) | RNPEPSMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL5471966 | 0.78 | ALDH1A1 (0.36) | MAPK1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL5469964 | 0.77 | ALDH1A1 (0.36) | RNPEPLMNAALDH1A1MAPTPTGS2 | |
| SCHEMBL5456318 | 0.77 | LAP3 (0.54) | LAP3ANPEPDNPEPRNPEPCAPN9 | |
| SCHEMBL5469548 | 0.76 | DNM1 (0.40) | HPGD | |
| SCHEMBL5471497 | 0.74 | RNPEP (0.53) | LAP3ANPEPDNPEPRNPEPCAPN9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070009462-A9 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | MALLE GERARD | 2007-01-11 | — | — | US | claimed |
| US-20050201964-A1 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | L'OREAL S.A. (FR) | 2005-09-15 | — | — | US | claimed |
| US-20070009462-A9 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | MALLE GERARD | 2007-01-11 | — | — | US | disclosed |
| US-20050201964-A1 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | L'OREAL S.A. (FR) | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050201964-A1 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | NR5A1, SRD5A2, HRH3 | LAP3 1217/4885ANPEP 3671/4885DNPEP 3764/4885 |
| US-20070009462-A9 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | NR5A1, SRD5A2, HRH3 | LAP3 1217/4885ANPEP 3671/4885DNPEP 3764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.