Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.68 |
| ▸ | HPGD | P15428 | 7/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
| ▸ | CASP7 | P55210 | 1/20 | 0.61 |
| ▸ | CNR2 | P34972 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3914054 | 0.82 | MAPT (0.82) | HSD17B10HPGDALDH1A1KDM4ENPSR1 | |
| SCHEMBL3923508 | 0.81 | MAPT (0.77) | HSD17B10HPGDALDH1A1KDM4ENPSR1 | |
| SCHEMBL3916162 | 0.81 | MAPT (0.80) | HSD17B10HPGDALDH1A1KDM4ENPSR1 | |
| SCHEMBL7892222 | 0.81 | MAPT (0.84) | HSD17B10HPGDALDH1A1KDM4ENPSR1 | |
| SCHEMBL8289604 | 0.80 | MAPT (0.78) | HSD17B10HPGDALDH1A1KDM4ENPSR1 | |
| SCHEMBL13561104 | 0.80 | MAPT (1.00) | HSD17B10HPGDALDH1A1KDM4ENPSR1 | |
| SCHEMBL3917114 | 0.80 | MAPT (0.82) | HSD17B10HPGDALDH1A1KDM4ENPSR1 | |
| SCHEMBL21247199 | 0.79 | MAPT (1.00) | HSD17B10HPGDALDH1A1KDM4ENPSR1 | |
| SCHEMBL16562058 | 0.79 | MAPT (0.80) | HSD17B10HPGDALDH1A1KDM4ENPSR1 | |
| SCHEMBL8290510 | 0.78 | MAPT (0.77) | HSD17B10HPGDALDH1A1KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225318-A1 | Pyrazole Compounds Useful In The Treatment Of Inflammation | BIOLIPOX AB (SE) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225318-A1 | Pyrazole Compounds Useful In The Treatment Of Inflammation | ALOX15, ALOX15B, ALOX12 | HSD17B10 762/4885HPGD 66/4885ALDH1A1 306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.