Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.49 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | MC1R | Q01726 | 1/20 | 0.46 |
| ▸ | NMBR | P28336 | 4/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | TACR3 | P29371 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | CTSC | P53634 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5470683 | 1.00 | KMT2A (0.53) | KMT2AMEN1MAPTNPC1POLB | |
| SCHEMBL5455335 | 0.84 | NMBR (0.52) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL5459435 | 0.82 | SIRT1 (0.61) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL5459439 | 0.82 | SIRT1 (0.61) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL8115065 | 0.80 | NMBR (0.72) | MAPTNMBRSIRT1TACR1SIRT2 | |
| SCHEMBL1711017 | 0.75 | ERAP2 (0.66) | MAPTPOLBALDH1A1ALOX15MAPK1 | |
| SCHEMBL8115081 | 0.73 | NPC1 (0.50) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL5464217 | 0.73 | HDAC1 (0.56) | NPC1RAB9APTGER4 | |
| SCHEMBL5462875 | 0.73 | RAB9A (0.59) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL5462870 | 0.73 | RAB9A (0.59) | KMT2AMEN1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070293530-A1 | SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | METHYLGENE INC. (CA) | 2007-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293530-A1 | SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC11, HAT1 | KMT2A 37/4885MEN1 3832/4885MAPT 2802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.