SCHEMBL313099

SCHEMBL313099

COc1ccc(C#N)cc1F

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AR P10275 3/20 0.51
LMNA P02545 1/20 0.46
MAPK1 P28482 1/20 0.46
HTT P42858 1/20 0.46
RAB9A P51151 1/20 0.46
NR3C1 P04150 1/20 0.45
PGR P06401 1/20 0.45
NR3C2 P08235 1/20 0.45
TUBB1 Q9H4B7 3/20 0.44
KDM1A O60341 3/20 0.43
KDM4E B2RXH2 1/20 0.43
USP2 O75604 1/20 0.43
ALDH1A1 P00352 1/20 0.43
USP30 Q70CQ3 1/20 0.43
CYP11B1 P15538 1/20 0.42
CYP11B2 P19099 1/20 0.42
SLC6A4 P31645 1/20 0.42
SLC6A9 P48067 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31128553 1.00 AR (0.51) ARLMNAMAPK1HTTRAB9A
SCHEMBL7285654 0.85 KIF11 (0.54) ARRAB9AKDM1AALDH1A1
SCHEMBL9061902 0.85 KIF11 (0.54) ARRAB9AKDM1AALDH1A1
SCHEMBL350999 0.84 AR (0.51) ARNR3C1PGRNR3C2KDM1A
SCHEMBL9644087 0.83 AR (0.59) ARRAB9ASLC6A4
SCHEMBL509522 0.81 AR (0.66) ARKDM1AKDM4EUSP2ALDH1A1
SCHEMBL29490258 0.81 AR (0.66) ARKDM1AKDM4EUSP2ALDH1A1
SCHEMBL12230360 0.80 AR (0.39) ARLMNAMAPK1HTTRAB9A
SCHEMBL2437123 0.80 RAB9A (0.46) LMNAMAPK1HTTRAB9ATUBB1
SCHEMBL16987880 0.80 USP30 (0.49) ARNR3C1PGRNR3C2USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118054087-B Electrolyte, electrolyte injection method and lithium metal battery 蜂巢能源科技股份有限公司 2024-07-19 CN claimed
CN-118054087-A Electrolyte, electrolyte injection method and lithium metal battery 蜂巢能源科技股份有限公司 2024-05-17 CN claimed
US-20170342070-A1 CYCLOPROPYLAMINES AS LSD1 INHIBITORS INCYTE CORPORATION 2017-11-30 US claimed
EP-3105218-A1 CYCLOPROPYLAMINES AS LSD1 INHIBITORS Incyte Corporation (US) 2016-12-21 EP claimed
WO-2015123465-A1 CYCLOPROPYLAMINES AS LSD1 INHIBITORS INCYTE CORPORATION (US) 2015-08-20 WO claimed
US-20150225401-A1 CYCLOPROPYLAMINES AS LSD1 INHIBITORS INCYTE CORPORATION (US) 2015-08-13 US claimed
US-20250129016-A1 PHOTOREDOX METHODS FOR RADIOCYANATION OF ARENES AND USE THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2025-04-24 US disclosed
CN-118054087-B Electrolyte, electrolyte injection method and lithium metal battery 蜂巢能源科技股份有限公司 2024-07-19 CN disclosed
EP-4395828-A1 BIFUNCTIONAL DEGRADERS COMPRISING A TEAD BINDER Novartis AG (CH) 2024-07-10 EP disclosed
CN-115677723-B 5-HT2A receptor antagonists and their use for treating central nervous system disorders 瀚远医药有限公司 2024-06-04 CN disclosed
CN-118054087-A Electrolyte, electrolyte injection method and lithium metal battery 蜂巢能源科技股份有限公司 2024-05-17 CN disclosed
WO-2024031089-A1 SARS-COV2 MAIN PROTEASE INHIBITORS GILEAD SCIENCES, INC. (US) 2024-02-08 WO disclosed
US-20230322758-A1 COMPOUNDS AS GLP-1R AGONISTS TERNS PHARMACEUTICALS, INC. 2023-10-12 US disclosed
US-4997942-A 2,4-disubstituted pyrazine derivatives, pyrimidine derivatives, and liquid crystal containing the same DAINIPPON INK AND CHEMICAL, INC. (JP) 1991-03-05 US disclosed
EP-0339252-A2 2,5-disubstituted pyrazine derivatives, pyrimidine derivatives, and liquid crystal containing the same DAINIPPON INK AND CHEMICALS, INC. (JP) 1989-11-02 EP disclosed
US-4865763-A LOW TEMPERATURE STABILITY CHISSO CORPORATION (JP) 1989-09-12 US disclosed
US-4765924-A SMECTIC PHASE FORMING INHIBITION CHISSO CORPORATION (JP) 1988-08-23 US disclosed
US-4710315-A USE WITH MULTIPLEXIBLE DISPLAYS HAVING HIGH DENSITY IMAGES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1987-12-01 US disclosed
EP-0233706-A2 Halogen-containing heterocyclic compounds and liquid crystal compositions containing them Chisso Corporation (JP) 1987-08-26 EP disclosed
WO-1985004874-A1 ANISOTROPIC COMPOUNDS AND LIQUID CRYSTAL MIXTURES THEREWITH MERCK PATENT GMBH (DE) 1985-11-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150225401-A1 CYCLOPROPYLAMINES AS LSD1 INHIBITORS KDM1B, KDM1A, KDM2A AR 937/4885LMNA 2442/4885MAPK1 3969/4885
US-20170342070-A1 CYCLOPROPYLAMINES AS LSD1 INHIBITORS KDM1B, KDM1A, KDM2A AR 937/4885LMNA 2442/4885MAPK1 3969/4885
US-20250129016-A1 PHOTOREDOX METHODS FOR RADIOCYANATION OF ARENES AND USE THEREOF RCC2, PPOX, FTO AR 53/4885LMNA 2919/4885MAPK1 2762/4885
US-20230322758-A1 COMPOUNDS AS GLP-1R AGONISTS GLP1R, GIPR, GCGR AR 853/4885LMNA 2472/4885MAPK1 777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.