SCHEMBL547138

SCHEMBL547138

CCCc1ccc(C(C)(C)C)cc1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.53
SIGMAR1 Q99720 3/20 0.47
LPL P06858 1/20 0.46
LIPG Q9Y5X9 1/20 0.46
TSHR P16473 2/20 0.46
GRIA4 P48058 1/20 0.46
PLK1 P53350 1/20 0.45
SLC13A5 Q86YT5 2/20 0.44
ESRRG P62508 2/20 0.44
DAO P14920 1/20 0.44
LMNA P02545 1/20 0.44
TYR P14679 1/20 0.44
TP53 P04637 1/20 0.44
BCHE P06276 1/20 0.43
ACHE P22303 1/20 0.43
CA2 P00918 1/20 0.43
ESRRB O95718 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12752950 0.89 KCNH2 (0.50) KCNH2SIGMAR1LPLLIPGGRIA4
SCHEMBL25044435 0.88 SLC22A2 (0.46) KCNH2SIGMAR1LPLLIPGTSHR
SCHEMBL7456580 0.87 KCNH2 (0.59) KCNH2SIGMAR1TSHRGRIA4SLC13A5
SCHEMBL547838 0.86 KCNH2 (0.60) KCNH2SIGMAR1PLK1ESRRGLMNA
SCHEMBL8776979 0.84 KCNH2 (0.63) KCNH2SIGMAR1LPLLIPGLMNA
Tert-Butylbenzene SCHEMBL10716886 0.84 RAB9A (0.49) KCNH2SIGMAR1ESRRGLMNATP53
SCHEMBL31573982 0.82 KCNH2 (0.67) KCNH2SIGMAR1TSHRGRIA4SLC13A5
SCHEMBL14393590 0.81 LPL (0.43) KCNH2LPLLIPGPLK1CA2
SCHEMBL17882028 0.81 LPL (0.43) KCNH2LPLLIPGPLK1CA2
SCHEMBL25009105 0.81 LPL (0.43) KCNH2LPLLIPGPLK1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115974730-A Method for synthesizing organic sulfate by persulfate 湖南大学 2023-04-18 CN disclosed
CN-107078352-B Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery using same 三菱化学株式会社 2020-04-28 CN disclosed
WO-2019070943-A1 SMALL MOLECULE INHIBITION OF TRANSCRIPTION FACTOR SALL4 AND USES THEREOF DANA-FARBER CANCER INSTITUTE, INC. (US) 2019-04-11 WO disclosed
CN-105580189-B Nonaqueous electrolyte solution and nonaqueous electrolyte battery using same 三菱化学株式会社 2017-09-22 CN disclosed
CN-107078352-A Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery using same 三菱化学株式会社 2017-08-18 CN disclosed
US-20160291461-A1 PATTERN FORMING METHOD, ELECTRONIC DEVICE MANUFACTURING METHOD, ELECTRONIC DEVICE, BLOCK COPOLYMER AND BLOCK COPOLYMER PRODUCTION METHOD FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
CN-105580189-A Nonaqueous electrolyte solution and nonaqueous electrolyte battery using same MITSUBISHI CHEM CORP 2016-05-11 CN disclosed
US-8110074-B1 Photochemical method for producing hydrocarbons NECKERS DOUGLAS C (US) 2012-02-07 US disclosed
US-20100234220-A1 Oxooxetanes as Fungicidal Agents BAYER CROPSCIENCE AG (DE) 2010-09-16 US disclosed
US-4929617-A INSECTICIDES, MITICIDES BASF AKTIENGESELLSCHAFT (DE) 1990-05-29 US disclosed
EP-0062368-B1 PERFUME COMPOSITIONS AS WELL AS PERFUMED PRODUCTS CONTAINING ALKYL SUBSTITUTED BENZYL CYANIDES AS A FRAGRANCE NAARDEN INTERNATIONAL N.V. (NL) 1984-08-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100234220-A1 Oxooxetanes as Fungicidal Agents CYP51A1, PNPO, AOX1 KCNH2 1671/4885SIGMAR1 3432/4885LPL 4121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.