SCHEMBL5471982

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8545963	0.88	PARP15 (0.45)	ARPOLBCACNA1GCACNA1BSLC6A4
	SCHEMBL5472622	0.87	AR (0.53)	ARPOLBGAACYP1A1CYP1B1
	SCHEMBL6295004	0.84	AR (0.55)	ARCACNA1GCACNA1BSLC6A4FFAR1
	SCHEMBL17472498	0.80	LTA4H (0.55)	POLBGAACYP1A1CYP1B1CA12
	SCHEMBL5475789	0.79	AR (0.50)	ARPOLBGAACYP1A1CYP1B1
	SCHEMBL27438050	0.79	AR (0.60)	ARPOLBGAACYP1A1CYP1B1
	SCHEMBL2788214	0.77	AR (0.55)	ARPOLBGAACACNA1GCACNA1B
	SCHEMBL921496	0.77	MAOA (0.56)	ARPOLBGAACACNA1GCACNA1B
	SCHEMBL30376409	0.75	AR (0.51)	ARPOLBSLC6A4HPGDSCA12
	SCHEMBL8546604	0.75	AR (0.51)	ARPOLBGAACACNA1GCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.