Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.44 |
| ▸ | PPARG | P37231 | 7/20 | 0.44 |
| ▸ | PPARD | Q03181 | 7/20 | 0.44 |
| ▸ | PPARA | Q07869 | 7/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Palmitic Acid SCHEMBL3252157 | 0.90 | GPR84 (0.63) | TSHRLMNAALDH1A1APEX1AKR1B1 | |
| Myristic Acid SCHEMBL3249423 | 0.90 | GPR84 (0.63) | TSHRLMNAALDH1A1APEX1AKR1B1 | |
| Palmitic Acid SCHEMBL6841075 | 0.90 | GPR84 (0.63) | TSHRLMNAALDH1A1APEX1AKR1B1 | |
| Dodecanoate SCHEMBL3249425 | 0.90 | GPR84 (0.63) | TSHRLMNAALDH1A1APEX1AKR1B1 | |
| Stearic Acid SCHEMBL3245114 | 0.90 | GPR84 (0.63) | TSHRLMNAALDH1A1APEX1AKR1B1 | |
| Decanoic Acid SCHEMBL8774854 | 0.90 | GPR84 (0.63) | TSHRLMNAALDH1A1APEX1AKR1B1 | |
| Glycinebetaine SCHEMBL1712631 | 0.88 | LMNA (0.58) | TSHRLMNAALDH1A1APEX1NFKB1 | |
| Glycinebetaine SCHEMBL9452080 | 0.84 | FFAR3 (0.56) | TSHRLMNAALDH1A1APEX1AKR1B1 | |
| Glycinebetaine SCHEMBL9281697 | 0.83 | TSHR (0.55) | TSHRLMNAALDH1A1APEX1MEN1 | |
| Glycinebetaine SCHEMBL3497624 | 0.83 | TSHR (0.46) | TSHRLMNAALDH1A1APEX1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297675-B2 | Process for the preparation of highly concentrated flowable aqueous solutions of betaines | GOLDSCHMIDT GMBH (DE) | 2007-11-20 | — | — | US | disclosed |
| US-20070015681-A1 | Process for the preparation of highly concentrated flowable aqueous solutions of betaines | GOLDSCHMIDT GMBH (DE) | 2007-01-18 | — | — | US | disclosed |
| US-7163916-B2 | Process for the preparation of highly concentrated flowable aqueous solutions of betaines | GOLDSCHMIDT GMBH (DE) | 2007-01-16 | — | — | US | disclosed |
| US-20060128599-A1 | Process for the preparation of highly concentrated flowable aqueous solutions of betaines | GOLDSCHMIDT GMBH (DE) | 2006-06-15 | — | — | US | disclosed |