Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5471761 | 0.87 | GUSB (0.33) | HRH4PIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL5477181 | 0.82 | PDE5A (0.38) | HRH4GUSBAR | |
| SCHEMBL13564574 | 0.79 | CYP2A6 (0.44) | HRH4PIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL5477167 | 0.73 | HRH4 (0.36) | HRH4PIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL5472664 | 0.73 | PDE5A (0.36) | GUSBARMEN1MAPTKMT2A | |
| SCHEMBL548410 | 0.72 | CYP2A6 (0.50) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL29149150 | 0.71 | TNKS (0.50) | CSNK2A2CSNK2BARCYP2C9KDM4E | |
| SCHEMBL16905656 | 0.70 | KDM4E (0.39) | HRH4PIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL11554110 | 0.69 | CYP2A6 (0.44) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL5471196 | 0.69 | KDM4E (0.60) | CSNK2A2CSNK2BHSD17B3KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070093548-A1 | Use of progesterone receptor modulators | WYETH (US) | 2007-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070093548-A1 | Use of progesterone receptor modulators | PGR, GNRHR, PGRMC2 | HRH4 1091/4885PIM1 4855/4885CSNK2A2 4136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.