Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29149097 | 0.84 | CSNK2A2 (0.52) | TNKSABCB1MAPTCYP3A4HPGD | |
| SCHEMBL312312 | 0.80 | MAPT (0.71) | TNKSARFTOMAPTCYP3A4 | |
| SCHEMBL30626951 | 0.80 | FTO (0.72) | TNKSARFTOABCB1MAPT | |
| SCHEMBL29114186 | 0.80 | FTO (0.72) | TNKSARFTOABCB1MAPT | |
| SCHEMBL29149084 | 0.80 | MAPT (0.67) | TNKSARABCB1MAPTCYP3A4 | |
| SCHEMBL38655536 | 0.71 | FTO (0.70) | TNKSARFTOABCB1MAPT | |
| SCHEMBL5475607 | 0.71 | HRH4 (0.34) | ARMAPTCYP3A4SMN1; SMN2CSNK2A2 | |
| SCHEMBL31387426 | 0.70 | TNKS (0.63) | TNKSFTOABCB1MAPTCYP3A4 | |
| SCHEMBL19744156 | 0.70 | ALDH1A1 (0.61) | TNKSMAPTHPGDRAB9ALMNA | |
| SCHEMBL11564846 | 0.70 | AR (0.53) | TNKSARMAPTCYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447402-A | Aromatic hydrocarbon receptor modulator compound, and preparation method and application thereof | 德明药泰生物技术（深圳）有限公司 | 2024-01-26 | — | — | CN | disclosed |