SCHEMBL547587

SCHEMBL547587

ClC(Cl)(OC(Cl)(Cl)c1ccccc1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.55
CYP1A2 P05177 1/20 0.44
KCNN4 O15554 5/20 0.42
MAPK1 P28482 1/20 0.42
ALDH1A1 P00352 2/20 0.41
ALOX15 P16050 1/20 0.39
BBOX1 O75936 1/20 0.35
EHMT2 Q96KQ7 1/20 0.35
EHMT1 Q9H9B1 1/20 0.35
KIF11 P52732 1/20 0.34
ORAI1 Q96D31 1/20 0.33
ORAI2 Q96SN7 1/20 0.33
ORAI3 Q9BRQ5 1/20 0.33
TRPV6 Q9H1D0 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
PTPN1 P18031 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL995346 0.82 TSHR (0.55) TSHRCYP1A2KCNN4MAPK1ALDH1A1
SCHEMBL10707751 0.78 TSHR (0.50) TSHRCYP1A2KCNN4MAPK1ALDH1A1
SCHEMBL7201481 0.78 TSHR (0.50) TSHRCYP1A2KCNN4MAPK1ALDH1A1
SCHEMBL1224334 0.78 TSHR (0.50) TSHRCYP1A2KCNN4MAPK1ALDH1A1
SCHEMBL9486963 0.77 TSHR (0.55) TSHRCYP1A2KCNN4MAPK1ALDH1A1
SCHEMBL9798410 0.76 TSHR (0.48) TSHRCYP1A2KCNN4MAPK1ALDH1A1
SCHEMBL11797488 0.74 TSHR (0.50) TSHRMAPK1
SCHEMBL1500477 0.73 TSHR (0.58) TSHRCYP1A2KCNN4MAPK1ALDH1A1
SCHEMBL2345811 0.72 CYP1A2 (0.52) TSHRCYP1A2KCNN4MAPK1ALDH1A1
SCHEMBL1683185 0.72 TSHR (0.44) TSHRCYP1A2KCNN4MAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116425705-A Application of solvent for co-production of maleic anhydride and succinic anhydride 上海师范大学 2023-07-14 CN disclosed
CN-110073507-B Organic semiconductor composition, organic thin film, and organic thin film transistor 日本化药株式会社 2023-07-04 CN disclosed
CN-113045519-B Solvent capable of simultaneously meeting production requirements of maleic anhydride and succinic anhydride and application thereof 上海师范大学 2023-05-16 CN disclosed
CN-112834640-B Method for separating and detecting components in permethrin 上海汉维生物医药科技有限公司 2022-08-30 CN disclosed
CN-114227834-A Processing method of insect-proof and moisture-proof wood board 彩智科技商贸(深圳)有限公司 2022-03-25 CN disclosed
US-8586020-B2 Poly(organophosphazene) composition for biomaterials KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2013-11-19 US disclosed
EP-2538780-A1 ESTROGEN RECEPTOR LIGANDS AND METHODS OF USE THEREOF Gtx, Inc. (US) 2013-01-02 EP disclosed
EP-2455362-A1 Nuclear receptor binding agents GTX, Inc. (US) 2012-05-23 EP disclosed
US-8158828-B2 Nuclear receptor binding agents GTX, INC. (US) 2012-04-17 US disclosed
US-8110203-B2 Adjuvant comprising non-toxic cross-linked muramyl dipeptide (MDP) microparticles derived from Propionibacterium acnes INNATE THERAPEUTICS LIMITED (NZ) 2012-02-07 US disclosed
EP-0276279-A1 COMPOSITION OF MATTER AND METHOD OF IMMUNIZING AGAINST VIRAL CAUSATIVE AGENTS OF AIDS AND ARC SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH (US) 1988-08-03 EP disclosed
US-4751064-A POLYPEPTIDE, HIGH MOLECULAR WEIGHT CARRIER YEDA RESEARCH & DEVELOPMENT CO., LTD. (IL) 1988-06-14 US disclosed
WO-1988000471-A1 COMPOSITION OF MATTER AND METHOD OF IMMUNIZING AGAINST VIRAL CAUSATIVE AGENTS OF AIDS AND ARC SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH (US) 1988-01-28 WO disclosed
EP-0245362-A1 SYNTHETIC PEPTIDES AND USE FOR DIAGNOSIS AND VACCINATION FOR AIDS AND ARC. SOUTHWEST FOUND BIOMED RES (US) 1987-11-19 EP disclosed
WO-1987002775-A1 SYNTHETIC PEPTIDES AND USE FOR DIAGNOSIS AND VACCINATION FOR AIDS AND ARC SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH (US) 1987-05-07 WO disclosed
EP-0082789-B1 IMMUNOLOGICAL COMPOSITION AND METHOD FOR HEPATITIS B VIRUS Baylor College of Medicine (US) 1987-04-08 EP disclosed
US-4444682-A OF HYDROXY AMINO ACIDS OR PEPTIDES CONTAINING SAME THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1984-04-24 US disclosed
EP-0082789-A2 Immunological composition and method for hepatitis B virus Baylor College of Medicine (US) 1983-06-29 EP disclosed
US-4387253-A Preparation of dichlorobenzyl alcohol THE BOOTS COMPANY LIMITED (GB) 1983-06-07 US disclosed
EP-0047622-A1 Preparation of dichlorobenzyl alcohol The Boots Company PLC (GB) 1982-03-17 EP disclosed