Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28729097 | 0.79 | TSHR (0.46) | TSHRMAPK1HIF1ALMNACYP2A6 | |
| SCHEMBL547587 | 0.74 | TSHR (0.55) | TSHRMAPK1 | |
| SCHEMBL4472039 | 0.73 | TSHR (0.57) | TSHRMAPK1HIF1ALMNACYP2A6 | |
| SCHEMBL5388132 | 0.73 | TSHR (0.57) | TSHRMAPK1HIF1ALMNACYP2A6 | |
| SCHEMBL196830 | 0.73 | TSHR (0.57) | TSHRMAPK1HIF1ALMNACYP2A6 | |
| SCHEMBL7782036 | 0.73 | CYP19A1 (0.65) | TSHRMAPK1HIF1ALMNACYP2A6 | |
| SCHEMBL28565817 | 0.69 | LMNA (0.57) | TSHRMAPK1HIF1ALMNACYP2A6 | |
| SCHEMBL28562858 | 0.69 | LMNA (0.57) | TSHRMAPK1HIF1ALMNACYP2A6 | |
| SCHEMBL8746597 | 0.69 | TSHR (0.59) | TSHRMAPK1HIF1ALMNACYP2A6 | |
| SCHEMBL677101 | 0.69 | MEN1 (0.59) | TSHRMAPK1HIF1ALMNACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3952065-A | ACTIVATED CARBON-PHOSPHORUS HALIDE OR AZO CATALYST, DECOMPOSITION | VYSKUMNY USTAV AGROCHEMICKEJ TECHNOLOGIE (CS) | 1976-04-20 | — | — | US | disclosed |