SCHEMBL5475894

SCHEMBL5475894

CCCCCCCCCCCCCCCCCCCCCC(=O)C(C[N+](C)(C)C)OP(=O)(O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 3/20 0.46
MAPK1 P28482 4/20 0.43
MAPT P10636 4/20 0.43
MEN1 O00255 3/20 0.43
GMNN O75496 3/20 0.43
LMNA P02545 3/20 0.43
KMT2A Q03164 3/20 0.43
NPSR1 Q6W5P4 3/20 0.43
TP53 P04637 3/20 0.43
TSHR P16473 3/20 0.43
CYP1A2 P05177 3/20 0.43
HSP90AA1 P07900 2/20 0.43
BLM P54132 2/20 0.43
NR1H4 Q96RI1 2/20 0.43
CYP2C9 P11712 2/20 0.43
HIF1A Q16665 2/20 0.43
SLC25A20 O43772 3/20 0.43
CYP2D6 P10635 2/20 0.43
GLA P06280 1/20 0.43
PMP22 Q01453 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1643924 1.00 SMPD1 (0.46) SMPD1MAPK1MAPTMEN1GMNN
SCHEMBL26927593 1.00 SMPD1 (0.46) SMPD1MAPK1MAPTMEN1GMNN
SCHEMBL27889175 0.92 FABP3 (0.50) SLC6A5CES2
SCHEMBL5916140 0.92 FABP3 (0.50) SLC6A5CES2
SCHEMBL30673761 0.88 MAPT (0.44) MAPK1MAPTMEN1GMNNLMNA
SCHEMBL30673768 0.88 MAPT (0.44) MAPK1MAPTMEN1GMNNLMNA
SCHEMBL31173704 0.88 MAPT (0.44) MAPK1MAPTMEN1GMNNLMNA
SCHEMBL5190821 0.88 MAPT (0.44) MAPK1MAPTMEN1GMNNLMNA
SCHEMBL28001919 0.87 MAPK1 (0.41) MAPK1MAPTMEN1GMNNLMNA
SCHEMBL28001916 0.87 MAPK1 (0.41) MAPK1MAPTMEN1GMNNLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8703179-B2 Mucosal formulation KIMBERLY-CLARK WORLDWIDE, INC. (US) 2014-04-22 US claimed
WO-2007133261-A1 MUCOSAL FORMULATION KIMBERLY-CLARK WORLDWIDE, INC. (US) 2007-11-22 WO claimed
US-20070264206-A1 Mucosal formulation KIMBERLY-CLARK WORLDWIDE, INC. 2007-11-15 US claimed
US-20260096985-A1 Injectable Composition For Drug Delivery CELANESE EVA PERFORMANCE POLYMERS LLC 2026-04-09 US disclosed
US-20260096984-A1 Implantable Device for Administering a Therapeutic Agent CELANESE EVA PERFORMANCE POLYMERS LLC (US) 2026-04-09 US disclosed
US-20260097150-A1 Implantable Device for Treating an Ocular Condition CELANESE EVA PERFORMANCE POLYMERS LLC (US) 2026-04-09 US disclosed
EP-4312951-A1 IMPLANTABLE MEDICAL DEVICE FOR THE DELIVERY OF NUCLEIC ACID-ENCAPSULATED PARTICLES Celanese EVA Performance Polymers LLC (US) 2024-02-07 EP disclosed
US-20220313616-A1 Implantable Medical Device for the Delivery of Nucleic Acid-Encapsulated Particles CELANESE EVA PERFORMANCE POLYMERS LLC 2022-10-06 US disclosed
WO-2022212300-A1 IMPLANTABLE MEDICAL DEVICE FOR THE DELIVERY OF NUCLEIC ACID-ENCAPSULATED PARTICLES CELANESE EVA PERFORMANCE POLYMERS LLC (US) 2022-10-06 WO disclosed
US-8703179-B2 Mucosal formulation KIMBERLY-CLARK WORLDWIDE, INC. (US) 2014-04-22 US disclosed
WO-2007133261-A1 MUCOSAL FORMULATION KIMBERLY-CLARK WORLDWIDE, INC. (US) 2007-11-22 WO disclosed
US-20070264206-A1 Mucosal formulation KIMBERLY-CLARK WORLDWIDE, INC. 2007-11-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097150-A1 Implantable Device for Treating an Ocular Condition P4HTM, ITGAM, TIMM44 SMPD1 2048/4885MAPK1 1634/4885MAPT 640/4885
US-20260096984-A1 Implantable Device for Administering a Therapeutic Agent GHITM, O60361, P4HTM SMPD1 1091/4885MAPK1 2896/4885MAPT 1202/4885
US-20070264206-A1 Mucosal formulation MUC1, CHMP4B, VMA21 SMPD1 145/4885MAPK1 1957/4885MAPT 1818/4885
US-20260096985-A1 Injectable Composition For Drug Delivery SAMM50, OPRM1, IRAK4 SMPD1 1480/4885MAPK1 2728/4885MAPT 559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.