Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5475914 | 1.00 | ALDH1A1 (0.35) | ALDH1A1TDP1HTT | |
| SCHEMBL4391808 | 0.85 | HTT (0.42) | ALDH1A1TDP1HTT | |
| SCHEMBL31448630 | 0.80 | ALDH1A1 (0.38) | ALDH1A1TDP1HTT | |
| SCHEMBL991349 | 0.79 | ALDH1A1 (0.33) | ALDH1A1TDP1HTT | |
| SCHEMBL9950848 | 0.78 | ALDH1A1 (0.36) | ALDH1A1TDP1HTT | |
| SCHEMBL9950853 | 0.78 | ALDH1A1 (0.36) | ALDH1A1TDP1HTT | |
| SCHEMBL10022735 | 0.78 | ALDH1A1 (0.36) | ALDH1A1TDP1HTT | |
| SCHEMBL11892004 | 0.78 | ALDH1A1 (0.36) | ALDH1A1TDP1HTT | |
| SCHEMBL143770 | 0.78 | ALDH1A1 (0.36) | ALDH1A1TDP1HTT | |
| SCHEMBL16314558 | 0.78 | ALDH1A1 (0.36) | ALDH1A1TDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275944-A1 | Antioxidants and methods of their use | THE BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2007-11-29 | — | — | US | disclosed |
| WO-2007117558-A2 | ANTIOXIDANTS AND METHODS OF THEIR USE | MICHIGAN STATE UNIVERSITY (US) | 2007-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275944-A1 | Antioxidants and methods of their use | GPX1, GPX4, SOD1 | ALDH1A1 408/4885TDP1 475/4885HTT 157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.