Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | ADK | P55263 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KCNK13 | Q9HB14 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3534451 | 0.72 | BRD4 (0.46) | NISCHALDH1A1SMN1; SMN2BRD4MTOR | |
| SCHEMBL2866599 | 0.67 | GAA (0.51) | LMNATDP1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL25395328 | 0.66 | — | — | |
| SCHEMBL36575 | 0.66 | — | — | |
| SCHEMBL81650 | 0.66 | NISCH (0.59) | NISCHALDH1A1SMN1; SMN2BRD4MTOR | |
| SCHEMBL5667704 | 0.66 | NISCH (0.50) | NISCHALDH1A1SMN1; SMN2MTORADK | |
| SCHEMBL2027445 | 0.66 | CSNK1A1 (0.43) | NISCHALDH1A1SMN1; SMN2BRD4MTOR | |
| SCHEMBL28796695 | 0.66 | NISCH (0.40) | NISCHALDH1A1SMN1; SMN2BRD4MTOR | |
| SCHEMBL27816158 | 0.66 | LMNA (0.46) | LMNATDP1NISCHALDH1A1SMN1; SMN2 | |
| SCHEMBL198066 | 0.66 | SMN1; SMN2 (0.42) | LMNATDP1SMN1; SMN2GAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070117948-A1 | Mixtures for producing reactive hot melt adhesives and reactive hot melt adhesives obtained on the basis thereof | ROEHM GMBH & CO. KG (DE) | 2007-05-24 | — | — | US | disclosed |