Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5341517 | 0.87 | SCN4A (0.40) | HDAC1HDAC2HDAC8HDAC6HDAC5 | |
| SCHEMBL413536 | 0.74 | GABRP (0.48) | HDAC1HDAC2HDAC8HDAC6HDAC5 | |
| SCHEMBL415236 | 0.72 | GABRA1 (0.65) | HDAC1HDAC2HDAC8HDAC6HDAC5 | |
| SCHEMBL13933893 | 0.71 | SCN4A (0.47) | CYP1A2HSD17B10CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL5342860 | 0.70 | SCN4A (0.39) | HDAC1HDAC2HDAC8HDAC6HDAC5 | |
| SCHEMBL27650272 | 0.70 | HPGD (0.42) | HDAC1HDAC2HDAC8HDAC6HDAC5 | |
| SCHEMBL2834175 | 0.69 | CYP19A1 (0.47) | HDAC1HDAC2HDAC8HDAC6HDAC5 | |
| SCHEMBL17261551 | 0.68 | KMT2A (0.47) | HDAC1HDAC2HDAC8HDAC6HDAC5 | |
| SCHEMBL21401830 | 0.67 | NR5A2 (0.45) | HDAC1HDAC2HDAC8HDAC6HDAC5 | |
| SCHEMBL5836525 | 0.67 | HDAC1 (0.52) | HDAC1HDAC2HDAC8HDAC6HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007089455-A1 | FLUOROALKENYL DERIVATIVES AS INSECTICIDES AND NEMATICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-08-09 | — | — | WO | disclosed |