Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 8/20 | 0.65 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.65 |
| ▸ | GABRP | O00591 | 3/20 | 0.65 |
| ▸ | GABRD | O14764 | 3/20 | 0.65 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.65 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.65 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.65 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.65 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.65 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.65 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.65 |
| ▸ | GABRE | P78334 | 3/20 | 0.65 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.65 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.65 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.65 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL413536 | 0.85 | GABRP (0.48) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL10247832 | 0.83 | GABRA1 (0.59) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL415468 | 0.82 | GABRA1 (0.47) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| Gabazine SCHEMBL5529434 | 0.79 | GABRA1 (1.00) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| Gabazine SCHEMBL5473649 | 0.78 | GABRA1 (0.98) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| Gabazine SCHEMBL16320027 | 0.77 | GABRA1 (0.95) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL24707043 | 0.77 | FFAR1 (0.47) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL29193525 | 0.75 | SRC (0.52) | GAAHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL2834175 | 0.75 | CYP19A1 (0.47) | HSD17B10HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL414508 | 0.75 | GABRP (0.40) | GABRA1GABRB2GABRPGABRDGABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022054-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | LABORATOIRE BIODIM (FR) | 2012-01-26 | — | — | US | disclosed |
| EP-2376431-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | LABORATOIRE BIODIM (FR) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010066847-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | CELLVIR (FR) | 2010-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022054-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | HAVCR2, MAVS, EIF2AK2 | GABRA1 3384/4885GABRB2 3283/4885GABRP 3362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.