Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 8/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5473684 | 1.00 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EHSD17B10FKBP1A | |
| SCHEMBL14581869 | 0.85 | ALDH1A1 (0.44) | ALDH1A1KDM4EHSD11B1MAPK1HTT | |
| SCHEMBL14581789 | 0.85 | HSD11B1 (0.43) | ALDH1A1HPGDKDM4EHSD17B10HSD11B1 | |
| SCHEMBL5481988 | 0.85 | HSD11B1 (0.43) | ALDH1A1HSD11B1LMNAKMT2AMEN1 | |
| SCHEMBL14581868 | 0.84 | HSD11B1 (0.42) | ALDH1A1HPGDKDM4EHSD17B10HSD11B1 | |
| SCHEMBL5471117 | 0.84 | POLB (0.42) | ALDH1A1HPGDKDM4EHSD17B10HSD11B1 | |
| SCHEMBL5471314 | 0.84 | LMNA (0.44) | ALDH1A1KDM4EHSD11B1MAPK1HTT | |
| SCHEMBL5468253 | 0.83 | HSD11B1 (0.39) | ALDH1A1HPGDKDM4EHSD17B10FKBP1A | |
| SCHEMBL5468378 | 0.83 | USP5 (0.42) | ALDH1A1HPGDKDM4EHSD17B10HSD11B1 | |
| SCHEMBL5473662 | 0.82 | HSD11B1 (0.41) | HSD11B1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070027118-A1 | Novel compounds of amino sulfonyl derivatives | AGOURON PHARMACEUTICALS, INC | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027118-A1 | Novel compounds of amino sulfonyl derivatives | HSD11B1, HSD11B2, HSD17B11 | ALDH1A1 74/4885HPGD 385/4885KDM4E 1163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.