Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | POLQ | O75417 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505610 | 0.85 | NPSR1 (0.40) | L3MBTL1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL2754138 | 0.82 | LMNA (0.37) | LMNAL3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28294173 | 0.81 | NPSR1 (0.38) | L3MBTL1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL14324469 | 0.80 | MKNK1 (0.40) | L3MBTL1MLYCDCYP3A4POLQALDH1A1 | |
| SCHEMBL27728396 | 0.80 | MEN1 (0.51) | MEN1KMT2ASMN1; SMN2NPSR1MLYCD | |
| SCHEMBL7827701 | 0.79 | NPSR1 (0.41) | L3MBTL1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL7747329 | 0.78 | MTNR1A (0.37) | L3MBTL1MEN1KMT2ASMN1; SMN2MLYCD | |
| SCHEMBL11400851 | 0.78 | MEN1 (0.42) | LMNAL3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1008397 | 0.78 | NPSR1 (0.44) | L3MBTL1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL3938034 | 0.76 | NPSR1 (0.43) | L3MBTL1MEN1KMT2ASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185148-A1 | M3 muscarinic acetylchoine receptor antagonists | GLAXO GROUP LIMITED (GB) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185148-A1 | M3 muscarinic acetylchoine receptor antagonists | CHRM3, CHRM2, CHRM5 | LMNA 3744/4885L3MBTL1 1306/4885MEN1 3632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.