Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5470537 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AHPGDPOLB | |
| SCHEMBL7147435 | 0.85 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AHPGDPOLB | |
| SCHEMBL11684446 | 0.81 | KMT2A (0.57) | ALDH1A1MEN1KMT2AHPGDPOLB | |
| SCHEMBL7300749 | 0.81 | TRPA1 (0.41) | ALDH1A1MEN1KMT2AHPGDPOLB | |
| SCHEMBL7277789 | 0.81 | TRPA1 (0.41) | ALDH1A1MEN1KMT2AHPGDPOLB | |
| SCHEMBL9708802 | 0.81 | TRPA1 (0.41) | ALDH1A1MEN1KMT2AHPGDPOLB | |
| SCHEMBL9708851 | 0.81 | TRPA1 (0.41) | ALDH1A1MEN1KMT2AHPGDPOLB | |
| SCHEMBL12285475 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2AHPGDPOLB | |
| SCHEMBL7154332 | 0.79 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AHPGDPOLB | |
| SCHEMBL24673548 | 0.78 | LMNA (0.53) | ALDH1A1MEN1KMT2AHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225246-A1 | O-acetyl-ADP-ribose non-hydrolyzable analogs | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225246-A1 | O-acetyl-ADP-ribose non-hydrolyzable analogs | PARP1, TIPARP, CD38 | ALDH1A1 1110/4885MEN1 4527/4885KMT2A 3126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.