SCHEMBL547752

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28521052	0.78	SOS1 (0.50)	PADI4HSD17B10HPGDTSHRNR4A1
	SCHEMBL28906694	0.77	CYP2D6 (0.51)	GPR35HSD17B10HPGDNR4A1NR4A2
	SCHEMBL25256056	0.77	HSD17B10 (0.52)	GPR35PADI4HSD17B10THRBHPGD
	SCHEMBL547788	0.76	SOS1 (0.51)	HSD17B10HPGDTSHRNR4A1NR4A2
	SCHEMBL548583	0.74	PADI4 (0.44)	PADI4THRBTSHRALDH1A1POLB
	SCHEMBL547679	0.74	PADI4 (0.44)	PADI4PARP1HSD17B10THRBHPGD
	SCHEMBL547751	0.73	KMT2A (0.41)	PADI4HSD17B10THRBHPGDALDH1A1
	SCHEMBL19253277	0.73	GPR35 (0.47)	GPR35PARP1HSD17B10THRBHPGD
	SCHEMBL10596069	0.72	GPR35 (0.59)	GPR35HSD17B10THRBHPGDCYP2C9
	SCHEMBL547541	0.71	IDO1 (0.47)	GPR35HSD17B10HPGDTSHRNR4A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.