SCHEMBL5477668

SCHEMBL5477668

Cc1ccc(-n2nc(C(F)(F)F)c3c2C(=O)N(c2ccc(N4CCCCC4=O)cc2)CC3)cc1CN

nearest known ligand 0.66

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.66
F2 P00734 6/20 0.66
SLC29A1 Q99808 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1997182 0.90 F10 (0.65) F10F2SLC29A1
SCHEMBL5482613 0.85 F10 (0.57) F10F2SLC29A1
SCHEMBL1999373 0.85 F10 (0.65) F10F2
SCHEMBL1998438 0.80 F10 (0.68) F10F2SLC29A1
SCHEMBL2003955 0.80 F10 (1.00) F10F2SLC29A1
SCHEMBL2004317 0.80 F10 (0.65) F10F2SLC29A1
SCHEMBL2001907 0.79 F10 (1.00) F10F2SLC29A1
SCHEMBL1995254 0.79 F10 (0.66) F10F2SLC29A1
SCHEMBL1998104 0.78 F10 (0.69) F10F2
SCHEMBL16189973 0.78 F10 (0.65) F10F2SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070060589-A1 Inhibitors of protein arginine methyl transferases BRISTOL-MYERS SQUIBB COMPANY 2007-03-15 US disclosed
WO-2006069155-A2 INHIBITORS OF PROTEIN ARGININE METHYL TRANSFERASES BRISTOL-MYERS SQUIBB COMPANY (US) 2006-06-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070060589-A1 Inhibitors of protein arginine methyl transferases PRMT1, PRMT3, PRMT6 F10 3866/4885F2 2641/4885SLC29A1 1878/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.