Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.57 |
| ▸ | F2 | P00734 | 6/20 | 0.57 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5477668 | 0.85 | F10 (0.66) | F10F2SLC29A1 | |
| SCHEMBL1997182 | 0.78 | F10 (0.65) | F10F2SLC29A1 | |
| SCHEMBL2004317 | 0.76 | F10 (0.65) | F10F2SLC29A1 | |
| SCHEMBL16190031 | 0.76 | F10 (0.50) | F10F2SLC29A1 | |
| SCHEMBL1999373 | 0.74 | F10 (0.65) | F10F2 | |
| SCHEMBL1998438 | 0.73 | F10 (0.68) | F10F2SLC29A1 | |
| SCHEMBL2003955 | 0.73 | F10 (1.00) | F10F2SLC29A1 | |
| SCHEMBL2001907 | 0.72 | F10 (1.00) | F10F2SLC29A1 | |
| SCHEMBL1995254 | 0.72 | F10 (0.66) | F10F2SLC29A1 | |
| SCHEMBL1998104 | 0.72 | F10 (0.69) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070060589-A1 | Inhibitors of protein arginine methyl transferases | BRISTOL-MYERS SQUIBB COMPANY | 2007-03-15 | — | — | US | disclosed |
| US-20070060589-A1 | Inhibitors of protein arginine methyl transferases | BRISTOL-MYERS SQUIBB COMPANY | 2007-03-15 | — | — | US | disclosed |
| US-20070060589-A1 | Inhibitors of protein arginine methyl transferases | BRISTOL-MYERS SQUIBB COMPANY | 2007-03-15 | — | — | US | disclosed |
| WO-2006069155-A2 | INHIBITORS OF PROTEIN ARGININE METHYL TRANSFERASES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060589-A1 | Inhibitors of protein arginine methyl transferases | PRMT1, PRMT3, PRMT6 | F10 3866/4885F2 2641/4885SLC29A1 1878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.