Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 6/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL158291 | 0.97 | LMNA (0.57) | LMNACYP2A6IDO1TSHRCYP1A2 | |
| Water SCHEMBL8070851 | 0.93 | LMNA (0.53) | LMNACYP2A6IDO1TSHRCYP1A2 | |
| Bromide SCHEMBL3139794 | 0.89 | TSHR (0.50) | LMNACYP2A6IDO1TSHRCYP1A2 | |
| Bromide SCHEMBL3129122 | 0.89 | TSHR (0.50) | LMNACYP2A6IDO1TSHRCYP1A2 | |
| SCHEMBL1535668 | 0.85 | TSHR (0.53) | LMNACYP2A6IDO1TSHRCYP1A2 | |
| SCHEMBL92023 | 0.85 | TSHR (0.53) | LMNACYP2A6IDO1TSHRCYP1A2 | |
| SCHEMBL3619478 | 0.85 | LMNA (0.44) | LMNACYP2A6IDO1TSHRCYP1A2 | |
| SCHEMBL35582410 | 0.85 | LMNA (0.44) | LMNACYP2A6IDO1TSHRCYP1A2 | |
| SCHEMBL12639140 | 0.83 | MAPK1 (0.50) | LMNACYP2A6CYP1A2MAPK1CYP3A4 | |
| SCHEMBL92018 | 0.83 | CES2 (0.48) | LMNACYP2A6CES2CES1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1431032-B1 | Polymerizable composition and lithographic printing plate precursor | FUJIFILM CORP (JP) | 2015-12-09 | — | — | EP | disclosed |
| US-8110337-B2 | Mixture of binder, an unsaturated compound and acid generator; lithography | FUJIFILM CORPORATION (JP) | 2012-02-07 | — | — | US | disclosed |
| EP-1840177-B1 | Ink set for ink-jet recording and ink-jet recording method | FUJIFILM CORP (JP) | 2010-03-24 | — | — | EP | disclosed |
| EP-1688467-B1 | Ink composition, inkjet recording method, printed material, method for producing planographic printing plate, and planographic printing plate | FUJIFILM CORP (JP) | 2008-06-25 | — | — | EP | disclosed |
| US-20070229637-A1 | Ink set for ink-jet recording and ink-jet recording method | FUJIFILM CORPORATION (JP) | 2007-10-04 | — | — | US | disclosed |
| EP-1840177-A1 | Ink set for ink-jet recording and ink-jet recording method | FUJIFILM Corporation (JP) | 2007-10-03 | — | — | EP | disclosed |
| US-20070166643-A1 | Photosensitive resin composition and manufacturing method of semiconductor device using the same | FUJIFILM CORPORATION (JP) | 2007-07-19 | — | — | US | disclosed |
| US-20060178449-A1 | Ink composition, inkjet recording method, printed material, method for producing planographic printing plate, and planographic printing plate | FUJI PHOTO FILM CO., LTD. | 2006-08-10 | — | — | US | disclosed |
| EP-1688467-A1 | Ink composition, inkjet recording method, printed material, method for producing planographic printing plate, and planographic printing plate | Fuji Photo Film Co., Ltd. (JP) | 2006-08-09 | — | — | EP | disclosed |
| US-20040137369-A1 | Polymerizable composition and lithographic printing plate precursor | FUJI PHOTO FILM CO., LTD. | 2004-07-15 | — | — | US | disclosed |
| EP-1431032-A1 | Polymerizable composition and lithographic printing plate precursor | FUJI PHOTO FILM CO., LTD. (JP) | 2004-06-23 | — | — | EP | disclosed |
| EP-0327194-B1 | SYNTHESIS OF TRIARYLSULPHONIUM SALTS | International Business Machines Corporation (US) | 1992-07-08 | — | — | EP | disclosed |
| US-4980492-A | Synthesis of triarylsulfonium salts | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1990-12-25 | — | — | US | disclosed |
| EP-0327194-A1 | Synthesis of triarylsulphonium salts | International Business Machines Corporation (US) | 1989-08-09 | — | — | EP | disclosed |