SCHEMBL5478180

SCHEMBL5478180

c1ccc(Sc2c[nH]c(Sc3ccccc3)n2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.43
HTT P42858 1/20 0.43
TUBB4A P04350 1/20 0.39
TUBB P07437 1/20 0.39
TUBA3C P0DPH7 1/20 0.39
TUBA1B P68363 1/20 0.39
TUBA4A P68366 1/20 0.39
TUBB4B P68371 1/20 0.39
TUBB3 Q13509 1/20 0.39
TUBB2A Q13885 1/20 0.39
TUBB8 Q3ZCM7 1/20 0.39
TUBA3E Q6PEY2 1/20 0.39
TUBA1A Q71U36 1/20 0.39
TUBA1C Q9BQE3 1/20 0.39
TUBB6 Q9BUF5 1/20 0.39
TUBB2B Q9BVA1 1/20 0.39
TUBB1 Q9H4B7 1/20 0.39
NCOA1 Q15788 1/20 0.38
NCOA3 Q9Y6Q9 1/20 0.38
DHFR P00374 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9214047 0.78 TUBB4A (0.38) HPGDHTTTUBB4ATUBBTUBA3C
SCHEMBL4864598 0.77 TUBB4A (0.37) HPGDHTTTUBB4ATUBBTUBA3C
SCHEMBL6627821 0.77 MEN1 (0.39) HPGDTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL8429277 0.69 HPGD (0.52) HPGDHTTNCOA1NCOA3DHFR
SCHEMBL6393359 0.68 HPGD (0.43) HPGDHTTNCOA1NCOA3DHFR
SCHEMBL17279762 0.68 DCUN1D1 (0.40) HPGDHTTDHFRCXCL12MAPT
SCHEMBL29223586 0.67 HPGD (0.50) HPGDHTTNCOA1NCOA3MAPT
SCHEMBL11583201 0.67 ALDH1A1 (0.48) HPGDHTTDHFRCXCL12ALDH1A1
Diphenylsulfane SCHEMBL31466756 0.67 HPGD (0.56) HPGDHTTTUBB4ATUBBTUBA3C
SCHEMBL5032699 0.65 MTOR (0.45) HPGDHTTTUBB4ATUBBTUBA3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7267892-B2 Electroluminescent devices having pendant naphthylanthracene-based polymers EASTMAN KODAK COMPANY (US) 2007-09-11 US disclosed
US-20070187673-A1 ELECTROLUMINESCENT DEVICES HAVING PENDANT NAPHTHYLANTHRACENE-BASED POLYMERS EASTMAN KODAK COMANY 2007-08-16 US disclosed