Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | DHFR | P00374 | 4/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.35 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17279762 | 0.82 | DCUN1D1 (0.40) | ALDH1A1KDM4EDHFREGFRTYMS | |
| SCHEMBL29196175 | 0.81 | NR1H2 (0.45) | ALDH1A1KDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL8727492 | 0.78 | DHFR (0.48) | DHFRTYMSHTT | |
| Water SCHEMBL11667040 | 0.72 | DAO (0.50) | ALDH1A1TSHRHTT | |
| SCHEMBL156748 | 0.69 | ALDH1A1 (0.37) | ALDH1A1KDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL8075774 | 0.69 | CXCL12 (0.53) | ALDH1A1KDM4EDHFREGFRTYMS | |
| SCHEMBL23207798 | 0.67 | CXCL12 (0.47) | ALDH1A1KDM4EDHFRTYMSKDM1A | |
| SCHEMBL5478180 | 0.67 | HPGD (0.43) | ALDH1A1KDM4EKMT2AMEN1DHFR | |
| SCHEMBL168083 | 0.66 | — | — | |
| SCHEMBL757019 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4128557-A | PHOTOGRAPHIC IMAGING MATERIAL | EASTMAN KODAK COMPANY (US) | 1978-12-05 | — | — | US | disclosed |
| US-4123274-A | SILVER HALIDE, SILVER SALT OF A 3-AMINO-5-ARYL(ALKYL)THIO-1,2,4-TRIAZOLE, DEVELOPER, BINDER; PHOTOTHERMOGRAPHY | EASTMAN KODAK COMPANY (US) | 1978-10-31 | — | — | US | disclosed |
| US-4113717-A | Quaternized azo dyestuffs | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-12 | — | — | US | disclosed |
| US-4111929-A | POLYACRYLONITRILE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-05 | — | — | US | disclosed |