SCHEMBL5478635

SCHEMBL5478635

C=C(CC1CNCCO1)C(=O)OCC

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 4/20 0.40
SLC6A4 P31645 3/20 0.40
ADRB2 P07550 1/20 0.40
HTR1A P08908 1/20 0.40
HTR2A P28223 1/20 0.40
ADRA1A P35348 1/20 0.40
HTR2B P41595 1/20 0.40
SLC6A3 Q01959 1/20 0.40
ADRA2C P18825 1/20 0.35
SSTR4 P31391 3/20 0.34
CHEK1 O14757 1/20 0.34
FECH P22830 1/20 0.34
KCNH2 Q12809 1/20 0.34
ALDH1A1 P00352 3/20 0.33
TSHR P16473 1/20 0.33
WNT1 P04628 1/20 0.31
GSK3B P49841 1/20 0.31
DYRK1A Q13627 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2921129 0.82 SLC6A2 (0.43) SLC6A2SLC6A4ADRB2HTR1AHTR2A
SCHEMBL30275082 0.82 SLC6A2 (0.43) SLC6A2SLC6A4ADRB2HTR1AHTR2A
SCHEMBL17627798 0.82 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL8492275 0.79 SLC6A1 (0.34) SLC6A2SLC6A4ADRB2HTR1AHTR2A
SCHEMBL156677 0.78 ALDH1A1 (0.49) ALDH1A1TSHR
SCHEMBL28650886 0.78 LMNA (0.43) ALDH1A1TSHR
SCHEMBL6574784 0.77 ALDH1A1 (0.34) ALDH1A1TSHR
SCHEMBL28338017 0.74 SLC6A2 (0.35) SLC6A2SLC6A4ADRB2HTR1AHTR2A
SCHEMBL5479797 0.74 ALDH1A1 (0.34) ALDH1A1TSHR
SCHEMBL17131035 0.74 SLC6A2 (0.42) SLC6A2SLC6A4ADRB2HTR1AHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7214247-B2 Polymers for laundry cleaning compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) 2007-05-08 US claimed
EP-1456261-A2 POLYMERS FOR LAUNDRY CLEANING COMPOSITIONS Unilever Plc (GB) 2004-09-15 EP claimed
US-20030130160-A1 Polymers for laundry cleaning compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-07-10 US claimed
WO-2003054044-A2 POLYMERS FOR LAUNDRY CLEANING COMPOSITIONS UNILEVER PLC (GB) 2003-07-03 WO claimed
US-7214247-B2 Polymers for laundry cleaning compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) 2007-05-08 US disclosed
EP-1456261-A2 POLYMERS FOR LAUNDRY CLEANING COMPOSITIONS Unilever Plc (GB) 2004-09-15 EP disclosed
US-20030130160-A1 Polymers for laundry cleaning compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-07-10 US disclosed
WO-2003054044-A2 POLYMERS FOR LAUNDRY CLEANING COMPOSITIONS UNILEVER PLC (GB) 2003-07-03 WO disclosed