SCHEMBL5479490

SCHEMBL5479490

C=CCNC(=O)C1CCCCC1(C(=O)NCC=C)C(=O)NCC=C

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.49
LMNA P02545 1/20 0.43
NPSR1 Q6W5P4 2/20 0.38
THRB P10828 1/20 0.36
ALDH1A1 P00352 3/20 0.36
MME P08473 1/20 0.34
MEN1 O00255 1/20 0.33
TSHR P16473 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPT P10636 1/20 0.33
KDM4E B2RXH2 1/20 0.32
POLB P06746 1/20 0.32
FAAH O00519 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23861292 0.71 KMT2A (0.84) KMT2ALMNANPSR1ALDH1A1TSHR
SCHEMBL11015380 0.70 KMT2A (0.81) KMT2ANPSR1ALDH1A1TSHRSMN1; SMN2
SCHEMBL29043353 0.68 KMT2A (0.84) KMT2ALMNANPSR1ALDH1A1TSHR
SCHEMBL994568 0.67 DGAT1 (0.33)
SCHEMBL8313919 0.67
SCHEMBL11319056 0.65 KMT2A (0.55) KMT2ALMNANPSR1ALDH1A1TSHR
SCHEMBL19198662 0.64 THRB (0.48) KMT2ALMNANPSR1THRBALDH1A1
SCHEMBL6152527 0.64 KMT2A (0.81) KMT2ALMNANPSR1ALDH1A1MEN1
SCHEMBL2143309 0.64 KMT2A (0.53) KMT2ALMNANPSR1ALDH1A1KDM4E
SCHEMBL27906279 0.64 KMT2A (0.53) KMT2ANPSR1ALDH1A1MEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7288262-B1 Composition comprising a cyclohexane-based compound, compound and use of said compound to structure a composition L'OREAL S.A. (FR) 2007-10-30 US disclosed
US-6726915-B2 DIAMIDE COMPOUNDS RETAINING GOOD COSMETIC PROPERTIES, IN PARTICULAR A CERTAIN LEVEL OF L'OREAL (FR) 2004-04-27 US disclosed
US-20030129211-A9 Cosmetic or pharmaceutical composition in solid form comprising bis-acyl-amides L'OREAL S.A. (FR) 2003-07-10 US disclosed
US-20020150602-A1 Cosmetic or pharmaceutical composition in solid form comprising bis-acyl-amides LIVOREIL AUDE (FR) 2002-10-17 US disclosed
EP-1068854-A1 Solid form composition comprising an oil and a specific gelling agent, process for cosmetic treatment and use of this compound L'OREAL (FR) 2001-01-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030129211-A9 Cosmetic or pharmaceutical composition in solid form comprising bis-acyl-amides FAAH, HRH1, HRH4 KMT2A 875/4885LMNA 2522/4885NPSR1 455/4885
US-20020150602-A1 Cosmetic or pharmaceutical composition in solid form comprising bis-acyl-amides FAAH, HRH1, HRH4 KMT2A 875/4885LMNA 2522/4885NPSR1 455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.