Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3667202 | 0.98 | — | — | |
| Iodide SCHEMBL3672824 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL6100055 | 0.97 | CRHR1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL3670743 | 0.87 | CRHR1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL920628 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL2045225 | 0.84 | EBP (0.31) | — | |
| Hydrochloric Acid SCHEMBL2049862 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL6483898 | 0.84 | POLB (0.32) | — | |
| Hydrochloric Acid SCHEMBL1194812 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL919913 | 0.83 | CRHR1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501784-B1 | INTEGRATED CHEMICAL PROCESSES FOR INDUSTRIAL UTILIZATION OF SEED OILS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-03-13 | — | — | EP | claimed |
| EP-1896385-B1 | METATHESIS PROCESS FOR PREPARING AN ALPHA, OMEGA -FUNCTIONALIZED OLEFIN | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-08-28 | — | — | EP | claimed |
| US-7816401-B2 | Process for total synthesis of pladienolide B and pladienolide D | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-10-19 | — | — | US | claimed |
| US-7812185-B2 | Metathesis process for preparing an alpha, omega-functionalized olefin | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-10-12 | — | — | US | claimed |
| US-7745652-B2 | Integrated chemical processes for industrial utilization of seed oils | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-06-29 | — | — | US | claimed |
| US-20090143544-A1 | INTEGRATED CHEMICAL PROCESSES FOR INDUSTRIAL UTILIZATION OF SEED OILS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-06-04 | — | — | US | claimed |
| US-20080262224-A1 | Method of Preparation of Benzofuran-2-Carboxylic Acid -Amide | SMITHKLINE BEECHAM CORPORATION | 2008-10-23 | — | — | US | claimed |
| US-20080228017-A1 | Metathesis Process For Preparing An Alpha, Omega-Functionalized Olefin | DOW GLOBAL TECHNOLOGIES INC. (US) | 2008-09-18 | — | — | US | claimed |
| EP-1935893-A1 | TOTAL SYNTHESIS OF PLADIENOLIDE B AND PLADIENOLIDE D | Eisai R&D Management Co., Ltd. (JP) | 2008-06-25 | — | — | EP | claimed |
| US-20080103346-A1 | Membrane Separation Of A Metathesis Reaction Mixture | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2008-05-01 | — | — | US | claimed |
| EP-1817097-A2 | MEMBRANE SEPARATION OF A METATHESIS REACTION MIXTURE | Dow Gloval Technologies Inc. (US) | 2007-08-15 | — | — | EP | claimed |
| US-20060167326-A1 | Stabilization of olefin metathesis product mixtures | ENERGY, UNITED STATES DEPARTMENT OF | 2006-07-27 | — | — | US | claimed |
| WO-2006047105-A2 | MEMBRANE SEPARATION OF A METATHESIS REACTION MIXTURE | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2006-05-04 | — | — | WO | claimed |
| EP-1363967-B1 | IMPROVED FIBER SUBSTRATE ADHESION TO ELASTOMERIC SUBSTRATES | LORD CORP (US) | 2006-04-12 | — | — | EP | claimed |
| US-20050154221-A1 | Integrate chemical processes for industrial utilization of seed oils | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION | 2005-07-14 | — | — | US | claimed |
| JP-2004519566-A | — | — | 2004-07-02 | — | — | JP | claimed |
| EP-1363967-A2 | IMPROVED FIBER SUBSTRATE ADHESION AND COATINGS BY METATHESIS POLYMERIZATION | Lord Corporation (US) | 2003-11-26 | — | — | EP | claimed |
| US-6525125-B1 | Molding material comprised of such as dicyclopentadiene resin and dimethylvinylmethylidene ruthenium dichloride catalyst; adjusting weight and balance of sports and marine equipment | MATERIA, INC. | 2003-02-25 | — | — | US | claimed |
| WO-2002077078-A2 | IMPROVED FIBER SUBSTRATE ADHESION AND COATINGS BY METATHESIS POLYMERIZATION | LORD CORPORATION (US) | 2002-10-03 | — | — | WO | claimed |
| US-20020015519-A1 | Fiber substrate adhesion and coatings by contact metathesis polymerization | LORD CORPORATION | 2002-02-07 | — | — | US | claimed |