Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 1/20 | 0.31 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.31 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL547963 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL2046729 | 0.83 | — | — | |
| Iodide SCHEMBL3672824 | 0.81 | — | — | |
| Bromide SCHEMBL3667202 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL6100055 | 0.81 | CRHR1 (0.31) | CRHR1 | |
| Hydrochloric Acid SCHEMBL2049862 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL3028477 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL2961475 | 0.75 | MAPT (0.36) | EBPDHCR7CRHR1 | |
| Hydrochloric Acid SCHEMBL920981 | 0.74 | — | — | |
| SCHEMBL1326589 | 0.74 | CYP3A4 (0.33) | EBPDHCR7C5AR1CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964685-B2 | Polymerizable composition | ZEON CORPORATION (JP) | 2011-06-21 | — | — | US | disclosed |
| US-20100144924-A1 | POLYMERIZABLE COMPOSITION | ZEON CORPORATION (JP) | 2010-06-10 | — | — | US | disclosed |
| US-20100015871-A1 | MOLDED ARTICLE, PROCESS FOR PRODUCING THE SAME, AND CROSSLINKED MOLDED ARTICLE AND COPPER-CLAD LAMINATE EACH OBTAINED THEREFROM | ZEON CORPORATION (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-2067812-A1 | MOLDED OBJECT, PROCESS FOR PRODUCING THE SAME, AND CROSSLINKED MOLDING AND COPPER-CLAD LAMINATE EACH OBTAINED FROM THE SAME | ZEON CORPORATION (JP) | 2009-06-10 | — | — | EP | disclosed |
| US-20070191563-A1 | Method of manufacturing thermoplastic resin, crosslinked resin, and crosslinked resin composite material | ZEON CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |