Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 18/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5479746 | 0.90 | HTR6 (0.74) | HTR6 | |
| SCHEMBL1136413 | 0.90 | HTR6 (0.70) | HTR6 | |
| SCHEMBL5482165 | 0.89 | HTR6 (0.67) | HTR6MEN1KMT2A | |
| SCHEMBL1536686 | 0.89 | HTR6 (0.61) | HTR6 | |
| SCHEMBL4473236 | 0.84 | HTR6 (1.00) | HTR6 | |
| SCHEMBL5483496 | 0.84 | HTR6 (0.71) | HTR6 | |
| SCHEMBL5485254 | 0.83 | HTR6 (0.64) | HTR6 | |
| SCHEMBL1136479 | 0.83 | HTR6 (0.68) | HTR6 | |
| SCHEMBL1136420 | 0.82 | HTR6 (0.72) | HTR6 | |
| SCHEMBL5480921 | 0.82 | HTR6 (0.62) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694656-B1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | HOFFMANN LA ROCHE (CH) | 2007-08-29 | — | — | EP | disclosed |
| US-7202241-B2 | Benzoxazine derivatives and uses thereof | ROCHE PALO ALTO LLC (US) | 2007-04-10 | — | — | US | disclosed |
| US-7202241-B2 | Benzoxazine derivatives and uses thereof | ROCHE PALO ALTO LLC (US) | 2007-04-10 | — | — | US | disclosed |
| US-7202241-B2 | Benzoxazine derivatives and uses thereof | ROCHE PALO ALTO LLC (US) | 2007-04-10 | — | — | US | disclosed |
| US-20050124613-A1 | Benzoxazine derivatives and uses thereof | ROCHE PALO ALTO LLC | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124613-A1 | Benzoxazine derivatives and uses thereof | XDH, CYP4X1, CYP2C9 | HTR6 1872/4885MEN1 2184/4885KMT2A 3126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.